Dermatology

Latest News


CME Content


For several years, a 71-year-old man has had a mildly pruritic rash on his legs that develops every winter and resolves when the weather becomes warmer. He is scheduled to undergo knee surgery, but the surgeon refuses to perform the operation until the rash has cleared.

Half way through a 15-minute iontophoresis treatment for de Quervain tenosynovitis of the right wrist, a 42-year-old woman felt exquisite pain but completed the session. After the therapist returned to the room and removed the electrodes, a light gray circular mark about 5 mm in diameter was noted on the skin. The epidermis was gone, and the underlying dermis was also injured. Within 6 hours, a tender, dark red-brown lesion developed.

Black discoloration appeared on the fingernails of a 51-year-old white man who had sustained burns on 15% of his body in a house fire 2 months earlier. The discoloration is a typical side effect of silver nitrate, which was applied to his skin and fingernails during the month he was hospitalized. This topical broad-spectrum bacteriostatic agent is used to reduce the risk of infection and mortality in burn patients.

For 3 months, a 24-year-old man-a military aviator-had a worsening rash on his chest. He had no lesions elsewhere. Culture of the ulcers grew Pseudomonas. A 2-week course of antibiotic therapy was ineffective.

A 48-year-old Hispanic man had a tender, bleeding growth within a darkly pigmented plaque on the right flank. The pigmented lesion had been present since birth; it was previously asymptomatic. The tumor arose out of the mainly flat patch 6 months earlier and had slowly enlarged. The patient worked indoors, wore sunscreen daily, and generally avoided outdoor activities. He had no family history of skin cancer.

A 37-year-old man presents with moderately pruritic urticarial papules on areas of his skin that are not covered by his shorts and T-shirt. He recently returned from a trip to Upstate New York, where he had stayed in several rustic cabins that were used by different people daily.

The red, 1- to 3-mm lesions on the right forearm of a 19-year-old man had recently become tender after being asymptomatic for 10 years. The patient described a shooting pain on palpation. Previous biopsy results showed no cancer. He had high blood pressure but was otherwise healthy. His father had similar lesions.

For 2 weeks, a 43-year-old white female had worsening nausea and multiple episodes of vomiting. Her symptoms began with increased malaise and decreased appetite. The emesis was unrelated to meals and was sometimes accompanied by mild abdominal distention. She had occasional fevers but denied any recent contact with ill persons. She also reported a 12-lb weight loss, decreased energy level, and an increased tan complexion over the past several months.

A 66-year-old woman was hospitalized because of severe anemia secondary to myelodysplastic syndrome. She had had associated fatigue and throbbing pain in both legs for several days.

A 20-year-old white male collegiate basketball player has a 3-year history of marked facial and upper extremity flushing that occurs after about 20 minutes of indoor practice. The flushing is preceded by an intense sensation of coldness, and despite the very noticeable flushing, the involved areas are cold to the touch for some time.

A 74-year-old woman presented with a refractory pruritic eruption. Four months earlier, she had sought evaluation of a thickened, slightly crusted 6 3 8-cm patch on her right ankle of 2 months' duration. Contact dermatitis with secondary impetigo from scratching was suspected, and a topical corticosteroid and an oral antibiotic were prescribed.