December 4th 2024
Your daily dose of the clinical news you may have missed.
December 2nd 2024
November 27th 2024
A woman in her early 50s presents with 6 hours of right sided pleuritic chest pain. What do the history and ECG suggest? What's yoru Dx?
November 26th 2024
The patient shows no signs of trauma but is a poor historian so no further details are available. Do her vitals or ECG provide any clues to a Dx?
November 25th 2024
Investigational Nasal Spray Found Safe, Effective for Self-Treatment of Paroxysmal Supraventricular Tachycardia
Etripamil 70 mg nasal spray restored heart rate within 30 minutes in approximately 60% of PSVT episodes, report authors of new study.
10 Questions on Adult Blood Pressure Targets Based on AAFP Guidelines
The 2022 AAFP Clinical Practice Guideline on hypertension treatment in adults is the subject matter for this 10-question topline quiz that is also a good source of review.
GLP-1 Mimetics, SGLT-2 Inhibitors Understudied in Black Populations in Pivotal Trials, Benefits Questioned
Pivotal cardiovascular outcome trials that evaluated cardiorenal benefits of the newer classes were not designed to consider racial/ethnic variations, researchers state.
Biosimilar Liraglutide Noninferior to Reference Product in Persons with Type 2 Diabetes: Phase 3 Trial
The biosimilar to the GLP-1 mimetic Victoza proved noninferior for reduction of HbA1c and had similar positive effects on body weight, lipids, and blood pressure.
Empagliflozin Wins FDA Approval for the Treatment of Adults with CKD
Empagliflozin is approved to lower the risk of sustained decline in eGFR, end-stage kidney disease, CV death, and hospitalization in adults with CKD at risk of progression.
Daily Dose: Antihypertensive Treatment Throughout Late Life Lowers Risk of Dementia
Waist-to-Hip Ratio More Consistently Associated with Mortality vs BMI: New Research
Waist-to-hip ratio was more powerfully and consistently associated with risk of all-cause mortality than BMI or FMI, but can it replace BMI as a clinical indicator?
USPSTF Publishes Final Guidance on Screening for Hypertensive Disorders of Pregnancy
The USPSTF recommends that BP be checked at all prenatal visits for all pregnant persons and calls for reducing vast inequities in maternal health care.
Daily Dose: Efficacy of a Remote Bilingual Program in Reducing Uncontrolled HTN
Novel Factor XI Inhibitor Abelacimab Found Superior to Rivaroxaban in Phase 2b Trial with High-Risk Cohort
The AZALEA-TIMI 71 trial was stopped early due to an "overwhelming reduction" in a composite endpoint of major bleeding events compared to rivaroxaban standard of care.
Antihypertensive Treatment Throughout Late Life May Reduce Risk of Dementia
Results from a new study show that older adults with untreated hypertension had a 42% increased risk of dementia vs healthy controls.
Daily Dose: High Blood Pressure While Lying Down Raises Risk for CVD Events
Daily Dose: "Night Owls" Less Healthy, at Higher Risk for T2D
Daily Dose: More Steps a Day Linked to Better Health for Patients with Heart Failure
Your daily dose of clinical news you may have missed.
Blood Pressure Treatment Targets in Adults with Hypertension: A Guideline Topline
This guideline topline summary of recommendations for treating hypertension in adults is adapted from the American Academy of Family Physicians clinical guideline.
Lorundrostat Phase 2 Trial Results Suggest Potential Efficacy Against Uncontrolled and Resistant Hypertension
The selective aldosterone synthase inhibitor will move into late stage clinical trials, a nod to the potential for a first-in-class agent targeting aldosterone.
Rise in GLP-1 Mimetic Demand Will Continue as Pluripotency Expands
The class of GLP-1 receptor agonists and similar agents, originally approved to treat type 2 diabetes, also reduce body weight and reduce CVD risk; what's next?
Evening Chronotype in Women Linked with Unhealthy Lifestyle, Increased Risk for Type 2 Diabetes
Women with an evening vs morning chronotype were 54% more likely to have unhealthy lifestyles that in turn accounted for a significant increased risk for diabetes.
Remote Bilingual Program Proves Effective in Controlling Blood Pressure in Underserved Population
New research presented at Hypertension 2023 showed a novel digital bilingual hypertension control program improved BP control rates by more than 30%.
Daily Dose: Worldwide Burden of Atrial Fibrillation Doubled Over 30 Years
Hypertension While Lying Down Linked to Elevated Risk for CVD Events
Persons with HTN while in a supine position had a higher risk for CVD even if they did not have HTN while seated, according to new research presented at Hypertension 2023.
Daily Dose: DAPT Should Remain Gold Standard for Percutaneous Coronary Intervention
The Worst States for Health Care in the US: 2023
Get a quick look at the US worst states for health care ranked using a composite score that included measures of cost, access, and outcomes.
Increased Step Count Tied to Better Health for Patients with Heart Failure
New research shows that patients with heart failure who had more steps per day and increasing steps per day experienced better health status over 12 weeks.
Daily Dose: Semaglutide 2.4 mg Benefits Patients with Heart Failure and Obesity
Daily Dose: Aspirin for Secondary Prevention of Cardiovascular Disease
Dual Antiplatelet Therapy Should Remain Gold Standard for Percutaneous Coronary Intervention, Say Authors of New Study
ESC 2023: New data showed an aspirin-free strategy after PCI did not reduce major bleeding event risk vs DAPT, while omission of aspirin proved noninferior for CV events in high-risk patients.
Biden Administration Announces First 10 Prescription Drugs Slated for Price Negotiations
The first 10 drugs identified for negotiations under the Inflation Reduction Act include several well advertised agents indicated to treat diabetes, heart failure, and other chronic diseases.
Dapagliflozin Did Not Meet Primary Endpoint in DICTATE-AHF Trial of Patients with Acute Decompensated Heart Failure
ESC 2023: Early initiation of dapagliflozin did not result in a statistically significant improvement in diuretic efficiency relative to structured usual care in patients hospitalized with ADHF.
Daily Dose: Semaglutide May Benefit 93 Million US Adults
A daily dose of clinical news on Patient Care you may have missed.