Substance-related Disorders

This second shelf-life extension for the OTC naloxone hydrochloride 4 mg spray continues the FDA's campaign to prevent drug overdose and related fatalities.

Screening for fibrosis in persons at risk of ALD and MASLD led to sustained improvements in lifestyle, eg, reduced alcohol consumption, weight loss, and increased exercise.

Your daily dose of the clinical news you may have missed.

Primary Care Alert: Risky alcohol use in the past year was found highest among persons taking benzodiazepines, followed by those taking opioids, and taking antiepileptics.

A daily dose of clinical news on Patient Care you may have missed.

Various illicit substances were detected in urine assays of 1 in 10 patients admitted to cardiac intensive care, according to findings of new French study.

A daily dose of clinical news you may have missed.

Binge drinking among women going through menopause has been on the rise, research indicates, making clinical inquiry in this population particularly important.

Black men experienced the highest rate of deaths related to cocaine while American Indian/Native Alaska communities were hit hardest by methamphetamine deaths.

July 4th invites celebration, typically with alcohol. Try our quiz based on a review of the holiday drinking patterns of US adults. Are answers to these 10 questions what you expect?

Your daily dose of clinical news you may have missed.

In a unique pharmacodynamic study, nalmefene demonstrated rapid reversal of respiratory depression from the synthetic opioid remifentanil and sustained duration of action.

The telehealth practice adopted in March 2020 at the start of the COVID public health emergency will be extended until November 11, 2023.

Updated VA/DoD chronic pain management guidelines include recommendations for dual use of buprenorphine and increased mental health assessment before prescribing opioids.

Nearly half of US adults aged 50 to 80 years report at least 1 symptom of addictive eating, a caution flag for primary care according to these experts.

An experimental program shows promise for better integration of screening for and treating alcohol use disorder into primary care practice.

Behavioral problems with food were found more common among women in their 50s and 60s and among men and women who report being lonely, in poor health, and overweight.

Yale Food Addiction Scale author Ashley Gearhardt, PhD, and National Poll on Healthy Aging director Jeffrey Kullgren, MD, MS, MPH, highlight new survey findings.

Food addiction researcher Ashley Gearhardt, PhD, highlights the criteria for substance addiction she has found apply equally to alcohol, cocaine, and highly processed foods.

Foods that are "engineered" with refined carbohydrates and fats that are rapidly absorbed can lead to cravings on par with those for alcohol and nicotine, says Ashley Gearhardt, PhD.

Intense craving for highly processed foods was so strong at least once a week for 24% of poll respondents that they couldn’t think of anything else.

A vaccine against fentanyl could stop the intense euphoria the drug creates and also block dangerous physiologic responses like respiratory depression, a new study suggests.

Gabapentin-involved overdose deaths doubled in Q2 2020 compared to Q1 2019, the CDC reports. What do you know, and maybe not know, about the troubling trend?

The ACP and AAFP along with 6 other professional groups say the current system is failing US mental health needs and it's time to make changes.

Approximately one-third of survey respondents with AUD relapsed within 1 year of stopping. Find a profile here of the experience of recovery from those who are trying.

More than one-third of survey respondents began drinking before age 15; the heaviest drinkers had double the risk for cirrhosis, CVD, pancreatitis, and neuropathy.

A new study of more than 2 million US adults and adolescents who could benefit from medication for OUD reveals only 1 in 4 reported past-year use.

Among persons who survived COVID-19, a new study found a 60% increased risk for any new mental health diagnosis during the year following infection.

Family physicians and psychiatrists were the specialties with the greatest number of visits, according to study authors.

The 100 000 drug overdose deaths in the US recorded for the period ended April 2021 paint a dire behind-the-scenes picture of life during COVID-19.