December 20th 2024
This marks the second indication for tirzepatide in just more than a year, following its November 2023 approval for adults with obesity or overweight and weight-related medical problems.
December 13th 2024
Your daily dose of the clinical news you may have missed.
December 2nd 2024
Review authors emphasized the need for a more comprehensive approach to dementia management.
November 26th 2024
June 24th 2024
ADA 2024. Adults with OSA and obesity receiving tirzepatide had improvements in sleep apnea severity and systolic blood pressure compared to placebo.
Effects of Common Analgesic Medications on Sleep: A Topical Review
Findings from a recent review highlight the impact of common analgesic medications on sleep patterns in people with chronic pain.
ADA 84th Scientific Sessions: 3 Studies Primary Care Clinicians Should Put on Their Radar
Details on tirzepatide for obesity-related obstructive sleep apnea, semaglutide for prevention of major kidney outcomes in patients with T2D and CKD, more.
ADA 84th Scientific Sessions Preview: STEP-HFp-EF Trial Data, Tirzepatide for Obesity-Related OSA, Optimizing Diabetes Care in Primary Care
Find details on optimizing diabetes care in primary care settings, benefits of GLP-1RAs for patients with HF and diabetes, and tirzepatide use for obesity-related OSA.
Tirzepatide Significantly Reduces OSA Symptoms in Phase 3 Trials, Lilly Looks Toward Mid-2024 Regulatory Submission
Tirzepatide reduced OSA symptoms and body weight in study participants with severe OSA and obesity, regardless of use of positive airway pressure therapy.
Women with Poor Sleep During Midlife at Significantly Elevated Risk for Future CVD
Women aged 40 to 65 years who had persistent insomnia and poor sleep duration were at a 75% greater risk for incident CVD over 2 decades of follow up.
Vagus Nerve Stimulation in Narcolepsy: Daily Dose
Vagus Nerve Stimulation Shows Promise Against Daytime Sleepiness in Narcolepsy: Novel Study
The effect of vagus nerve stimulation persons with narcolepsy revealed a specific, notable improvement in daytime sleepiness in a novel open-label study.
Dupilumab Reduces Nighttime Symptoms, Sleep Disturbance in Severe T2 Asthma
Use of dupilumab also eliminated the need for use of a rescue inhaler in more than one-third of treated patients and the number of inhalations needed for others.
Daily Dose: "Night Owls" Less Healthy, at Higher Risk for T2D
Opioids, Pain, and Sleep: How Do They Interact With Each Other?
A recent study of patients with chronic low back pain sheds light on the association between sleep and opioid use on pain severity and interference.
Evening Chronotype in Women Linked with Unhealthy Lifestyle, Increased Risk for Type 2 Diabetes
Women with an evening vs morning chronotype were 54% more likely to have unhealthy lifestyles that in turn accounted for a significant increased risk for diabetes.
Screen Patients with Obesity for These 2 CVD Risk Factors, Says One Expert
Obesity medicine specialist and internist Alina Elperin, MD, shares why screening for obstructive sleep apnea and metabolic disease in patients with obesity is crucial.
Cluster Headache, Migraine Show Strong Links to the Circadian System: Meta-analysis
Cluster headache and migraine are described as "highly circadian at multiple levels," suggesting hypothalamus involvement and potential for new treatments, study authors say.
Insomnia Associated with Significant Risk for MI, Should be Designated a CV Risk Factor
ACC 2023. A large study found increased risk for MI regardless of age and detected particularly heightened risk among women and persons with diabetes who have insomnia.
Irregular Sleeping Habits Associated with Measures of Subclinical Atherosclerosis in New Study
Sleep duration irregularity was associated with measures of subclinical atherosclerosis in a racially and ethnically diverse study of more than 2000 adults.
Daily Dose: Sleep Apnea May Raise Risk of Certain Cardiovascular Diseases
Your daily dose of clinical news you may have missed.
Sleep Apnea and Snoring Linked to Higher Risk of Hypertension, Coronary Artery Disease in New Study
A 2-sample Mendelian randomization analysis showed that sleep apnea and snoring increased the risk of HTN and CAD, and these associations may partly be driven by BMI.
Daily Dose: Benzodiazepines for Sleep Disorders Linked to Increased Risk for Drug Overdose among Youth
Benzodiazepines for Sleep Disorders Linked to Increased Risk for Drug Overdose among Youth
New findings suggest that the elevated risk of overdose with benzodiazepine use for sleep disorders is a critical safety consideration when treating young people.
Nocturnal Hypertension: 8 Essential Questions
Nocturnal HTN is a risk factor for cardiovascular disease and stroke. How do you diagnose and treat in your practice? Test your overnight BP IQ.
Sleep & Obesity: How to Prescribe Better Sleep for Patients
Educating patients with obesity about the link between poor sleep and weight gain is crucial. Review 5 key elements for achieving better sleep, here.
Poor Sleep Linked to Increased Risk of Cardiovascular Disease in Middle Adulthood
New study showed adults who provided sleep health data and wore a research device during sleep had a 141% increased risk of cardiovascular disease.
Sleep Duration May Have Greater Cardiometabolic Impact on Women vs Men
Results of a new study that used early clinical surrogate markers of metabolic disease find women at greater risk related to suboptimal sleep.
Pandemic-induced Sleep Disturbance Affects More than Half of US Adults
"COVID-somnia," defined as a group of chronic sleep disturbances, has made adequate rest elusive for millions, including health care first responders.
Patients with Severe OSA at Two-fold Higher Risk for Sudden Death, New Study Shows
Results of a new systematic review and meta-analysis by researchers at Penn State College of Medicine underscore needs for patient education and additional research on prevention.
Irregular Sleeping Patterns Linked to Depression, Bad Mood in First-Year Medical Students
Irregular sleeping patterns can increase risk of depression and lower daily mood over the long term, according to a new study of first-year medical students.
Sleep Disorders and Chronic Pain
Pain specialist Steven King, MD, highlights a new review that looks at the complex, bidirectional relationship between sleep disturbance and chronic pain.
Climate Change Health Hazards Quiz
Test your knowledge of the products of climate change and the health effects they may have.
Climate Change Is a Health Hazard: 8 Examples
Increases in diabetes, insomnia, and skin cancer are just 3 of the hazardous trends identified in recent research. More findings in our slide show.
New OSA Testing Guideline, Summarized
Obstructive sleep apnea ups the risk for many other health issues. Click through a 6-slide summary of updated recommendations.