December 20th 2024
This marks the second indication for tirzepatide in just more than a year, following its November 2023 approval for adults with obesity or overweight and weight-related medical problems.
December 13th 2024
Diabetic Peripheral Neuropathic Pain: Effective Management
July 26th 2012For many patients with diabetic peripheral neuropathy, severe pain can be controlled to a degree sufficient to improve their quality of life. Here: effective management strategies, including topical agents, oral medications, and nonpharmacological therapies (eg, acupuncture and transcutaneous nerve stimulation).
Obesity Hypoventilation Syndrome: Simple to Diagnose, Potentially Deadly if Overlooked
May 2nd 2012Obesity hypoventilation syndrome (OHS) shares clinical symptoms with obstructive sleep apnea (OSA) such as daytime sleepiness, headaches, and memory problems. Both the symptoms and their sequelae, however, can be much more severe in OHS. Here, guidance on what to look for and how to manage OHS.
All Ears: Chondrodermatitis Nodularis Helicis and Verruca Vulgaris
March 28th 2012Diagnostic challenge: Two case reports of easily treated and innocuous causes of lesions in the outer ear. Chondrodermatitis nodularis helicis is associated with long cellphone use. Verruca vulgaris is caused, like all other warts, by human papillomavirus.
How to Cope With Burnout: Diversify and Conquer
November 2nd 2011I recently read a study in JAMA entitled “Quality of Life, Burnout, Educational Debt, and Medical Knowledge among Internal Medicine Residents.” Over half (51.5%) of the 15,000 medical residents in the study cohort reported overall burnout and high levels of emotional exhaustion and depersonalization.
Understanding Sleep-Disordered Breathing and Its Impact on GI Disease
November 1st 2011Following on the heels of the obesity epidemic, a second epidemic has become apparent-sleep-disordered breathing and its effect on esophageal conditions, primarily gastroesophageal reflux disease (GERD). Many, many primary care providers have heard the following complaint: “I gained 10 pounds and now I have heartburn/cough/worsening asthma” (take your pick). What’s going on?
Obesity: Epidemiology and Medical Management
November 1st 2011Prevalence for overweight (BMI 24.9 to 29.9) and obesity (BMI > 30) have been steadily rising for the past 30 years-two-thirds of Americans now qualify as overweight or heavier. Hypertension, hyperlipidemia, coronary artery disease, type 2 diabetes, sleep apnea, and GERD prevalence are following this epidemic. Obesity is now the second most common preventable cause of death, exceeded only by smoking.
Association Between Sleep Disorders and GERD Explored at ACG Meeting
October 27th 2011Mention GERD and most of patients probably think of heartburn. But the GERD story does not begin and end with the esophagus. The connection between GERD and laryngeal, pharyngeal, and pulmonary symptoms is the focus of a seminar, “An Eye and Nose Opening Experience-Chronic Complications of GERD,” at the upcoming American College of Gastroenterology Annual Scientific Meeting, October 31 to November 2 in Washington, DC.
An Elderly Man With a Lung Mass and Neurologic Symptoms
September 28th 2011A 71-year-old man was admitted to the MICU for weaning from mechanical ventilation. The history revealed a global decline over the previous 3 to 4 weeks predominated by cognitive impairment, mood swings, somnolence, and limb weakness. No respiratory symptoms were noted.
Antihypertensives at Night: When You Snooze, You Lose?
September 15th 2011Typically, antihypertensive medications are taken in the morning. But typically does not always equal correct! Preliminary studies have documented that a more appropriate approach would be to take them (or at least some of them) at bedtime.