December 2nd 2024
Your daily dose of the clinical news you may have missed.
November 27th 2024
A woman in her early 50s presents with 6 hours of right sided pleuritic chest pain. What do the history and ECG suggest? What's yoru Dx?
November 26th 2024
The patient shows no signs of trauma but is a poor historian so no further details are available. Do her vitals or ECG provide any clues to a Dx?
November 25th 2024
November 22nd 2024
FLOW Trial: Semaglutide Lowers Risk for Major Kidney Disease, CV Events and Death Regardless of SGLT-2i Use
ADA 2024. Semaglutide benefits were observed for adults with type 2 diabetes and chronic kidney disease whether or not they used SGLT-2 inhibitors, according to an analysis of FLOW trial data.
Sugar Substitute Raises Risk of Major Adverse Cardiovascular Events: Daily Dose
SURMOUNT-OSA: Tirzepatide Improves Sleep Apnea Symptoms, CV Outcomes in Adults with OSA and Obesity
ADA 2024. Adults with OSA and obesity receiving tirzepatide had improvements in sleep apnea severity and systolic blood pressure compared to placebo.
Pemvidutide Preserves Lean Mass With Weight Loss of Nearly 16%: MOMENTUM Phase 2 Trial
ADA 2024. MOMENTUM trial findings presented at the ADA yesterday showed 78.1% of weight loss attributable to loss of fat vs lean mass in adults with overweight or obesity.
After ACS, Long-Term Lipid Management for FH Suboptimal in Women Compared to Men
Fiver years after ACS, a new study shows women are less likely to be on lipid lowering therapy and to meet LCL-C target levels than men.
George L Bakris, MD, Expert in Hypertension and Metabolic Disease, Has Died
Described as a giant and a pioneer in the hypertension and metabolic fields, Bakris is also remembered so fondly by colleagues as a very special man.
Chronic Hypertension in Pregnancy Increased Two-Fold Between 2008 and 2021
The doubling of the diagnosis of chronic hypertension in pregnancy was accompanied by no increase in treatment rates, according to a new study.
New Report Shows that Despite Gains, Black Americans Still Face Higher Cardiovascular Mortality
Between 2000 and 2022, there were nearly 800 000 excess CV deaths among Black Americans and 24 million additional years of life lost, researchers report.
Investigational RNAi Agent Cuts Triglyceride Levels in Patients with Mixed Hyperlipidemia: Daily Dose
Adolescent Obesity Linked to Higher Stroke Risk in Women: Daily Dose
Sugar Alcohol Xylitol Associated with Increased Risk of MACE: Cleveland Clinic Research
As xylitol is used increasingly to replace sugar in an array of food and other products, Clinic reselinic researchers call for increased scientific scrutiny rchers call for increased scrutiny..
Women with Overweight/Obesity as Teens, Young Adults Face Higher Risk of Cerebrovascular Disease Later in Life
In contrast, men did not face the same increased risk of cerebrovascular disease later in life, reported authors of a new study.
Two Medication Classes Reduce CV, Liver Events in Persons with T2D, MASLD: Daily Dose
GLP-1RAs, SGLT-2 Inhibitors Tied to Lower Adverse Cardiovascular and Liver Events in Persons with T2D, MASLD
ENDO 2024. New findings suggest GLP-1RAs and SGLT-2is may be more beneficial than other diabetes agents for patients with T2D and MASLD.
Ultraprocessed Foods Raise Risk for Cardiometabolic Issues in Children: Daily Dose
Plozasiran, an Investigational RNAi Therapy, Reduces Triglyceride Levels in Adults with Mixed Hyperlipidemia
Plozasiran, in the phase 2b MUIR trial, significantly reduced triglyceride and triglyceride rich lipoprotein levels through targeted action against APOC3.
Ultraprocessed Foods Raise Risk for Cardiometabolic Issues in Children, According to New Research
Findings underscore a need for public health initiatives to educate vulnerable populations on cardiometabolic risks, researchers report.
New Study Shows Men with Diabetes Have Higher Risk of Disease-related Complications than Women
Men with diabetes had a greater risk of CVD, lower limb and kidney complications, and diabetic retinopathy compared to women with diabetes.
Cardiovascular-Kidney-Metabolic Syndrome in the US: Daily Dose
SGLT2i Use and Improved QoL, Functional Capacity in Adults With HF: Daily Dose
Semaglutide Supports Long-Term Weight Loss, Reduces CV Risk Across BMI Subgroups
Analyses of the SELECT trial found mean weight loss of 10.2% sustained for 4 years and comparable CV benefit with weight loss greater or less than 5%, or even weight gain.
May Issue of Patient Care Online Digital Edition is Now Live
Find details on a novel web tool found to help patients determine their eligibility for OTC statin use, FDA clearance of the first AI-based algorithm to detect HF during routine exams, and more.
Poor Cardiovascular-Kidney-Metabolic Health “Widespread” among US Adults, According to New Study
Results also showed that older adults, men, and Black adults face an increased risk of advanced stages of CKM syndrome.
Children with HTN Have 2-times Higher Risk of Major Adverse Cardiac Events, According to New Research
Findings suggest that optimizing care for children with hypertension may reduce the risk of adult CVD, report researchers.
SGLT2 Inhibitor Use Improves Quality of Life, Functional Capacity in Patients with Heart Failure
Patients with HF who received SGLT2i therapy had significant improvement in functional capacity and QOL, regardless of sex, diabetes status, or ejection fraction, report researchers.
Atrial Fibrillation May be More Common in Younger Adults than Previously Thought: Daily Dose
Novel Web App for OTC Statin Medication: TACTiC Study Lead Author Steven Nissen, MD, Explains Findings
Dr Nissen discusses the impetus behind the study, the potential public health implications of the results, and more.
Cardiovascular-Kidney-Metabolic (CKM) Syndrome Affects Nearly All US Adults
The majority of the US adult population meets criteria for subclinical CKM syndrome indicating "an urgent need for population-wide risk reduction measures."
Poor Cardiovascular Health at Midlife Linked to Cognitive Decline in Black Women
Poor cardiovascular health at midlife was associated with a decline in the mental processing speed of Black women, but not White women, according to a new study.
Elevated Lp(a) Level Raises ASCVD Risk Regardless of Age, Sex, Race/Ethnicity: Daily Dose