In Crohn Disease, Biologic Dose Escalation is Common During Maintenance Phase, Study Reveals
"A meaningful percentage" of individuals with Crohn disease are treated during maintenance with biologic doses ≥20%higher than recommended in FDA labeling.
Migraine-related Stigma is Common and Impacts Level of Disability, Quality of Life
Reports of migraine-related stigma were common in a recent population-based study, with nearly one-third reporting the experience often/very often.
Gabapentinoid Use Increasing in US Despite Concerns Over Coprescribing, Off-Label Use
Gabapentinoid use increased from 4.0% of the population reporting use of the medication in 2015 to 4.7% in 2021, according to new data.
Daily Dose: Childhood Stress & Risk for Cardiometabolic Disease
Your daily dose of the clinical news you may have missed.
Baseline HbA1c Greater than 6.0% Linked to "Exponential" Increase in T2D Risk for Adolescents with Obesity
Adolescents with overweight or obesity and baseline HbA1c 6.3%-6.4% were at 72-fold greater risk for T2D than those with HbA1c of 5.5%, a new cohort study finds.
Gastro Pop Quiz: Endoscopic Evaluation in Crohn Disease
A 10-second check of your GI IQ.
Contraceptive Services Must be Provided without Cost-Sharing: HHS Guidance Update
Targeting "impermissible" barriers created to no-cost contraception required by the ACA, the HHS guidance follows the Biden-Harris June 2023 Executive Order on the issue.
New Research Suggests Outpatient C. difficile May be Underdiagnosed in US
Findings showed a high incidence of outpatient Clostridioides difficile infection despite a low rate of testing.
7 Questions on Biomarkers for Management of Crohn Disease
When does management of Crohn disease warrant assessment of C-reactive protein and fecal calprotectin and when is endoscopy indicated? Test your IBD IQ.
Daily Dose: Disparities in Inflammatory Bowel Disease
FDA Adds Black Box to Prolia PI Warning of Severe Hypocalcemia Risk in CKD
The Boxed Warning reflects FDA research into severe adverse events including hospitalization and death in persons with CKD treated with denosumab.
Diabetes Remission of Any Duration May Reduce Risk of Renal and Cardiovascular Disease:
Remission of T2D, regardless of duration of remission, was associated with reduced risk of diabetes-related CKD and CVD in a post hoc analysis of Look AHEAD.
Newly FDA-Authorized Diabetes Digital Therapeutic Can be Cost-Effective, According to Modeling Study
The digital prescription therapeutic when used along with prescription diabetes therapies, can help reduce the costs of managing the disease and enhance standard of care.
Where is All the Wegovy Going? Highest and Lowest Prescribing States
The GLP-1 RAs Wegovy, Ozempic, Mounjaro, and Zepbound have taken up more real estate on the US map in some areas than others. Click to find out more.
Vaccination Provides Moderate Protection against Long COVID in Children
Vaccination against SARS-CoV-2 was associated with reduced risk of long COVID for at least 12 months in children and adolescents in a new large retrospective study.
Vaccination Snapshots: COVID-19 and Beyond
Click through a short slideshow review of the available COVID-19 vaccines for adults and children and of the long COVID symptoms to watch for in all your patients.
Daily Dose: Lack of Osteoporosis Screening, Treatment in Patients with Cirrhosis
Rapid POC Test for 3 Pediatric Respiratory Viruses: Quick Survey
Tell us what features you would find most valuable in a rapid point-of-care test for simultaneous detection of respiratory viruses in pediatric patients.
Gabapentinoids May Increase Risk of Severe COPD Exacerbations, Warns New Study
In persons with COPD, use of the anticonvulsants was linked to a 39% increase in risk of severe disease exacerbation requiring hospital admission, study authors reported.
Hey Doc: Use or Lose those Vacation Days
Vacation behavior among US physicians was found wanting, with more than half taking less than 15 days/year, 20% taking ≤5 days, and 70% working on their time off.
