Dupilumab Plus Medium-Dose Inhaled Corticosteroid Improved Lung Function and Asthma Control, According to New Data
AAAAI 2024. Patients with asthma who received dupilumab plus medium-dose ICS had improved lung function and asthma control vs those who received placebo plus high-dose ICS.
Dupilumab Effective Up to 5 Years in Adults with Moderate-to-Severe Atopic Dermatitis in Open-Label Extension Study
AAAAI 2024. Reduction of AD signs and symptoms was significant among approximately half of study participants at 4 weeks and continuously rose through week 260, investigators report.
First Study of Oral Mucosal Immunotherapy for Peanut Allergy Elicits Robust Immunologic Response in Adults
AAAAI 2024. Oral mucosal immunotherapy delivered via metered-dose toothpaste produced a statistically significant increase in IgG4 and a decrease in IgE/IgG4 ratio.
Tighter Glycemic Control in T2D Reduces Risk for All-Cause Dementia: Daily Dose
Your daily dose of the clinical news you may have missed.
Tezepelumab Demonstrates Sustained Post-Treatment Reductions in CSU Disease Activity, Inflammatory Markers
AAAAI 2024. The effects, seen 18 to 20 weeks after discontinuation of tezepelumab, suggest a persistent effect of thymic stromal lymphopoietin (TSLP) blockade in CSU.
Salt Substitute Lowers Risk of Hypertension among Older Adults with Normal Blood Pressure
Older adults with normal BP levels in China were approximately 40% less likely to develop HTN when using a salt substitute for 2 years, according to a new study.
Women with IBD at Risk for Reduced Fertility Even During Clinical Disease Remission, Study Suggests
Histologic inflammation was associated with reduced fertility whether IBD disease was active or quiescent in a nationwide study of Swedish women aged 15 to 44 years.
SGLT2 Inhibitors Outperformed Other Oral Antidiabetic Drugs for Persons with T2D, NAFLD: Daily Dose
Omalizumab Granted First FDA Indication for Children and Adults with Multiple Food Allergies
The OUtMATCH trial showed that individuals as young as age 1 year could tolerate small amounts of peanut and other allergens without an allergic reaction.
Atlantic Health System Tests Novel CAR-T Cell Therapy for Lupus in First US Patient
In the open-label, phase 1 study, participants' own T cells will be extracted and engineered to target and eliminate autoreactive B cells and to potentially reset the immune system.
Apixaban and Aspirin Equal in Preventing Stroke Recurrence in Cardiopathy: Daily Dose
COPD Outcomes: Sedentary Lifestyle Significantly Increases Risk for ED Visits, Hospitalization
Conversely, increases in physical activity of just 500 METs/mins/week reduced respiratory ED visits or hospitalizations by 10-14%, according to a Korean study.
Weight Management Treatments Underused among Primary Care Patients with Obesity Despite Their Effectiveness
In a new study of primary care patients with obesity, bariatric surgery offered the greatest probability of 1-year weight loss of ≥5%, at 93%.
COVID-19 Hospitalization Raises Long-Term Mortality Risk Compared to Seasonal Flu: Daily Dose
Of Vaccine Efficacy and COVID-19 Variants: 4 Questions
Just when the new monovalent COVID-19 vaccines were available in Sept 2023, a new variant emerged. Did the CDC get it right? What do you know about the monovalent VE?
CDC: One-Third of Children in US Received an HPV Vaccine Dose
According to a new CDC report, 38.6% of children aged 9-17 years received ≥1 doses of the HPV vaccine in 2022.
Eating Disorder Hospitalizations Increasing among US Adolescents: Daily Dose
Abrysvo or Beyfortus: 2 Questions and Several Facts You Should Know
Should you pregnant patient get the new RSV vaccine at the appropriate time during gestation or wait and have the baby receive Beyfortus after birth?
T2D Remission After Gastric Bypass Persists, Despite Weight Regain
People with T2D and obesity who had gastric bypass surgery maintained significant levels of disease remission, despite up to 100% weight regain, study finds.
New Scientific Statement from American Heart Association Raises Awareness of CVD Risks for Women
Women with adverse pregnancy outcomes face a significantly higher risk of cardiovascular disease and stroke later in life, according to the statement.
