Panelists discuss how early screening, timely intervention, and the use of teplizumab can improve outcomes for individuals with type 1 diabetes (T1D) by delaying disease progression and reducing complications like diabetic ketoacidosis.
EP. 1: Examining the Burden of T1D
Panelists highlight the burden of type 1 diabetes including the significant physical, emotional, and financial challenges faced by patients and their families, emphasizing the need for early intervention and proactive management strategies.
EP. 2: Referral and Screening for Progression
Panelists discuss how delaying intervention between stage II and stage III T1D can result in irreversible β-cell loss, higher rates of complications, and poorer overall outcomes for patients.
EP. 3: Stages of T1D Progression
Panelists discuss how understanding the stages of type 1 diabetes (T1D) progression is crucial for early intervention, with a focus on delaying disease advancement through proactive treatments like teplizumab.
EP. 4: Consequences of Delaying Intervention
Panelists discuss how delaying intervention in stage 2 T1D can lead to faster disease progression, increased risk of complications like diabetic ketoacidosis, and greater long-term burden on patient health and quality of life.
EP. 5: Antibody Screening for T1D
Panelists discuss how antibody screening for type 1 diabetes can identify at-risk individuals early, enabling proactive monitoring and intervention to delay or prevent disease onset.
EP. 6: Teplizumab Therapy to Delay Onset and Progression of T1D
Panelists discuss how teplizumab therapy can delay the onset and progression of type 1 diabetes (T1D) by preserving β-cell function and reducing the risk of developing full-blown diabetes in at-risk individuals.
EP. 7: Teplizumab Use in Practice
Panelists discuss clinical use of teplizumab including patient selection, navigating approval processes, and managing the 14-day infusion regimen to optimize outcomes and delay the progression of type 1 diabetes.
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