Skin Diseases

The parents of a 12-year-old sought a consultation for the “cyst” that had appeared on their daughter's lower back. The lesion was first noticed 2 months earlier upon the child's return from a trip to Belize.

An 8-year-old boy was taken to his physician because of a rash around his mouth. After spending the day at the beach with his family, his lips had become red, itchy, and swollen. His sister had a similar, although milder, condition. Both children had been sucking on limes while at the beach. One week later, the boy experienced the chapped lips, patchy perioral erythema, swelling, and blisters.

Benign skin tumors seen in pregnant patients as well as those who are not pregnant include acrochordons, seborrheic keratoses, pyogenic granulomas, and spider angiomas. There have been reports that melanocytic nevi develop or change during pregnancy; however, a pilot study at our institution was unable to confirm this finding.

A 58-year-old black woman sought evaluation of areas of increased pigmentation on her cheeks that had been present for many years. Bleaching agents did not lighten the area; new, non–nickel-containing eyeglass frames had no effect. A 3-week course of halobetasol cream failed to fade the hyperpigmentation.

A 30-year-old anesthesiologist complained of 5 days of pain in the left epitrochlear and axillary regions. A large, tender node was palpable in each site.

A 63-year-old man was given oral celecoxib, 100 mg bid, for shoulder pain. Three days later, a pruritic rash appeared on his back, then spread to the chest, lower legs, and face. He stopped the celecoxib on his own and self-administered diphenhydramine for the pruritus. The rash and itch persisted, which prompted the patient to seek medical care. He had no respiratory symptoms.

A 32-year-old man presented with a yellow, papular rash on the buttocks and extensor surfaces. His medical history included diabetes mellitus, alcoholism, obesity, and polysubstance abuse. Laboratory results disclosed a serum triglyceride level of 5,793 mg/dL.

A 62-year-old woman presented with an itchy, annular eruption on her face of 3 months' duration. A topical antifungal was prescribed, but the slow response to therapy prompted a switch to a topical corticosteroid (triamcinolone 0.1%). The lesion not only failed to clear but became larger.

For about 4 months, a very dry, diffuse, fine scaly, asymptomatic eruption covered the palms of a 28-year-old man; several fingernails were dystrophic bilaterally as well. Before the onset of this condition, bilateral onychomycosis of the toenails had been diagnosed.

Low-potency corticosteroids had not resolved a rash of several month's duration on the buttocks of a 2-year-old girl.

A 6-year-old girl with mental retardation was seen for a physical examination. She was being followed by a neurologist for seizures that began in her first year of life. She had no acute health problems.

Consultation was sought for diagnosis of the concentric rings of erythema and scaling that appeared on one side of a 42-year-old woman's face. The patient had used a moderately potent topical corticosteroid that had been prescribed for a facial "rash."

Several hours after returning from a walk in tall grass, a 9-year-old boy began to complain about intense itching around his waist, lower back, and upper arms. Wheals developed on these areas.

For 2 months, an asymptomatic rash had been present on the upper arms of a 16-year-old boy of normal weight. The rash, as seen on the patient's right arm, consisted of abundant fine papules. He had no other lesions.

Each spring for the past 3 years, this boy has complained of an itchy ear rash. The dull red edematous papules develop on the outer portion of the helix, and the rash heals promptly after 2 weeks.

This asymptomatic pigmented lesion on the left posterior jaw of a 52-year-old man had been present for 6 years, with no evidence of recent change. At the patient's request, the lesion was excised.

HIV infection was diagnosed in a 34-year-old man 3 years before he was hospitalized. The patient had a 2-week history of nausea; vomiting; and diffuse, intermittent, poorly localized abdominal pain. He had received radiotherapy and chemotherapy for Kaposi's sarcoma (KS) of the upper and lower extremities, which had been diagnosed 8 months earlier.

A male infant was born to a 29-year-old woman (gravida 3, para 2), following an uncomplicated pregnancy and normal vaginal delivery. At birth, a brownish 1-cm nodule was noted on the right side of the upper abdomen. The infant was otherwise healthy.

A 3-mm long, double-tipped, polypoid lesion appeared just anterior to the anus on an 8-month-old girl 2 days earlier. The lesion was excised in the office: a local anesthetic was administered, and the base was lightly electrodesiccated. Antibiotic ointment was applied until the area healed. Pathologic findings identified an infantile perianal pyramidal protrusion.

A 16-year-old boy removed a small sliver of wood from the palm of his hand with a pocket knife. However, the fledgling “surgeon” created a small puncture wound during this operation. Over the next month, a small, moist, friable papule grew at the site.

A 19-year-old man was admitted to the hospital with malaise, fatigue, and intermittent fever (temperature of 38°C [100.4°F]) for the last 2 weeks. Physical examination revealed scarce purpuric lesions over the lower extremities; a pericardial friction rub was audible over the precordium when the patient was supine and seated, and the spleen was remarkably enlarged.

A 60-year-old white man was evaluated for dyspnea on exertion. Hepatomegaly and abnormal skin pigmentation were noted, particularly in the upper extremities.

A 49-year-old man was concerned about a right flexor forearm lesion that had been increasing in size for 6 weeks. The light pink, well-demarcated, 5-cm, circular lesion featured slight peripheral elevation with ulceration, crusting, and a relatively clear central area. A culture of material from the lesion was negative for fungi. A potassium hydroxide evaluation was not performed.

A 30-year-old woman had an extensive psychiatric history of anxiety and depression. She was concerned that the numerous lesions on her body might be signs of possible infection or infestation. The patient was undergoing treatment for multiple addictions to drugs, primarily methamphetamine (“crank”).

The persistent effects of Graves disease were evident in a 48-year-old woman who had recently emigrated from Haiti to the United States. Thyrotoxicosis had developed several years before she sought treatment in her native country. The patient's obstructive goiter was removed and treatment with thyroxine was begun.

A 6-year-old boy had a nonpruritic rash on his back for 10 days. There was no associated fever. The child's mother had placed a bandage over the lesions to prevent transmission to her other children.

Levofloxacin, 500 mg/d, had been prescribed for a 74-year-old woman who had a urinary tract infection. The patient had type 2 diabetes and hypertension. She was allergic to sulfa drugs.

This rash, which covered a 68-year-old woman's body, was noted to have worsened during the past 2 months. A cephalosporin antibiotic had failed to clear the condition. The patient, a nursing home resident, suffered from emphysema, asthma, and heart disease. She had been receiving oxygen therapy and prednisone for 1 year.

A 45-year-old African American man requested treatment of “keloids” that had developed 18 months earlier. The patient also complained of dyspnea and exertion; there was no history of trauma.

A brownish red, reticulate rash had persisted on the thighs of a 53-year-old man for about 15 years. For the past 20 years, he had applied-daily and for extended periods-a hot water bottle on his legs for soreness following exercise.