November 11th 2024
Insights on how to manage the "triple threat" of flu, RSV, and COVID-19 this season.
October 31st 2024
Your daily dose of the clinical news you may have missed.
October 29th 2024
Preliminary phase 1 data showed that RSV neutralizing antibodies for non-adjuvanted SCB-1019 matched GSK’s AS01E-adjuvanted RSV vaccine, Arexvy.
October 9th 2024
Data on adults aged 60 years and older who received a single dose of the RSV vaccine indicate safety and reactogenicity consistent with the overall GSK phase 3 trial program.
October 8th 2024
Breathlessness in Middle-Aged Adults Linked to Overweight/Obesity, Stress, and Respiratory Disease
Results of a recent study support the importance of lifestyle interventions to reduce the burden of breathlessness in middle-aged adults.
Pfizer: MONeT Study Topline Data Positive for Abrysvo in Adults Aged 18 to 59 Years at High Risk for RSV-LRTD
Pfizer plans to submit the phase 3 MONeT data to regulatory bodies in support of an expanded label for Abrysvo to include adults aged 18 to 59, the company said.
Vaccination of Older Adults Against RSV Could Reduce Symptomatic Cases by 1 Million per Year: Modeling Study
The study looked at the impact over 3 years but found that most of the averted burden, including more than 8000 fewer deaths, occur in the first year after vaccination.
Boehringer Ingelheim Will Cap Out of Pocket Costs for Inhalers at $35 per Month
The monthly out of pocket cap applies to all BI inhalers and goes into effect on June 1, 2024.
CDC: Persons with COVID-19, Flu, RSV, Other Respiratory Viruses No Longer Have to Isolate for 5 Days
The updated guidelines reflect the progress made in protecting against severe illness from COVID-19, said CDC Director Mandy Cohen, MD, MPH.
Abrysvo Efficacy Sustained in Older Adults Through Second RSV Season
The bivalent vaccine demonstrated "durable efficacy" of more than 80% over 2 RSV seasons, according to Pfizer's report of topline findings from the RENOIR trial.
ACIP Recommends Monovalent COVID-19 Booster for Older Adults this Spring
COVID-19 hospitalizations have never fall below 6000/week, according to the ACIP; those aged 65+ have the highest inpatient rate, those aged 75+ have the highest mortality.
8 Questions on the 2024 GOLD COPD Guidelines: A Quiz for Primary Care
Test your COPD IQ with these 8 questions on spirometry in COPD diagnosis, COPD exacerbations and treatment response, when to add ICS, and other topics for PCPs.
Impact of Regular Exercise on Hospitalization in Patients with COPD: Daily Dose
New Research Highlights Specific Allergens that May Predispose Sensitized Children with Asthma to Upper Respiratory Infections
AAAAI 2024. Indoor mouse and cockroach, but not cat and dog, allergen exposure were associated with URI outcomes among children with asthma.
COPD Outcomes: Sedentary Lifestyle Significantly Increases Risk for ED Visits, Hospitalization
Conversely, increases in physical activity of just 500 METs/mins/week reduced respiratory ED visits or hospitalizations by 10-14%, according to a Korean study.
COPD Management & Pharmacotherapy: A GOLD Guideline Topline
Get GOLD Report updates at-a-glance on initiating pharmacotherapy, avoiding exacerbations, treating dyspnea, how to approach using ICS, plus other topics.
Influenza Vaccines: 4 Questions on What to Order, Which to Use
Influenza continues to rage in some parts of the US; try these 4 quick questions on vaccines you may or may not have on hand.
The 2024 COPD GOLD Report: A Guideline Topline, Part 1
Updates in the Global Initiative for Obstructive Lung Disease report include using spirometry values in diagnosis and optimizing inhaled pharmacotherapy.
Combination Albuterol/Budesonide Rescue Medication for Adults with Asthma Now Available
The combination SABA/ICS inhaler is the first of its kind and treats both acute bronchoconstriction and the inflammation that drives asthma and disease exacerbation.
Risk for Incident Asthma and Exacerbations Increases with Atopic Dermatitis in Dose-Dependent Fashion: Study
The risk of asthma and poor outcomes was even greater among children with both conditions than among adults in this first study to compare the 2 populations.
Daily Dose: Gabapentinoids & Risk of Severe COPD Exacerbations
Gabapentinoids May Increase Risk of Severe COPD Exacerbations, Warns New Study
In persons with COPD, use of the anticonvulsants was linked to a 39% increase in risk of severe disease exacerbation requiring hospital admission, study authors reported.
Daily Dose: Hospitalization for COVID-19 vs for Flu Linked to More Long-Term Outcomes
Two RSV Vaccines, One Savvy Patient who Asks, "Which One do You Recommend?"
RSV vaccines from Pfizer-BioNTech and Moderna for adults aged 60 years and older aren't that different, so which would you recommend if a patient asks?
COPD Exacerbations May Increase Risk of Severe CV Events by More Than 15-Fold: Cohort Study
The risk of severe CV events, including leading to death, was greatest in the first week following an exacerbation but remained significantly elevated 1 year later.
Daily Dose: Higher Omega-3 Fatty Acid Intake May Slow Pulmonary Fibrosis Disease Progression
Hospitalization for COVID-19 vs for Influenza Linked to More, More Severe Long-Term Outcomes: Study
After hospital discharge, persons who had COVID-19 remained at greater risk of death and myriad adverse health outcomes compared with those who had seasonal flu.
Moderna mRNA RSV Vaccine for Adults Returns Positive Phase 3 Results
Moderna's investigational vaccine against RSV in adults showed mean efficacy of 83% against the infection and is the only mRNA technology-based RSV shot.
EPA, DHA May Have Protective Effects in Pulmonary Fibrosis
Higher serum levels of the omega-3 fatty acids were associated with slowed disease progression and longer transplant-free survival in a new study.
FDA Grants Priority Review to Merck BLA for Investigational 21-Valent Pneumococcal Vaccine
If approved the 21-valent shot would be the first pneumococcal conjugate vaccine indicated specifically for adults.
Daily Dose: Coadministration of RSV and Influenza Vaccines
Coadministration of RSV, Influenza Vaccines Found Safe and Effective in New Study
The coadministration of RSVpreF and seasonal influenza vaccine was found to generate robust immune responses in older adults, reported authors of new study.
Paxlovid Associated with Virologic Rebound in One in Five Patients with Severe COVID-19 Infection
The finding implies the potential for virus transmission after initial recovery from the infection, according to study authors.
CDC Core Elements of Outpatient Antibiotic Stewardship: The Quiz
According to the US CDC, the most important modifiable risk factor for antibiotic resistance is (fill in this blank). Find out here and fill in 5 more blanks.