Tezepelumab May Improve Peak Expiratory Flow in Patients with Severe Asthma, Suggests Analysis of NAVIGATOR Trial
CHEST 2021: Patients with severe asthma who received tezepelumab compared with placebo demonstrated rapid improvement in morning and evening peak expiratory flow.
Heart Failure Milestones in Management: 9 Studies Making a Difference in 2021
SGLT-2 inhibitors have proven effective in disease modification as well as symptom improvement across HF phenotypes and severity. Get a quick summary of the research.
COVID-19 Updates: Delta Variant, US Vaccinations, & Global Data as of October 13, 2021
Data from the CDC on the Delta variant and US vaccination rates and from the Johns Hopkins COVID-19 interactive map on cases and deaths in the US and worldwide.
FDA to Food Industry: Cut Sodium in Processed and Packaged Foods
The FDA issued new guidance today providing short-term sodium reduction targets for food manufactures, chain restaurants, and food service operators.
Inappropriate Patient Requests: How do you Get to No?
Fielding inappropriate patient requests and getting to "No" while preserving rapport with a patient is an essential clinical skill. AAFP has a 5-step approach.
USPSTF Shift: Aspirin Use for Primary CVD Prevention Carries Greater Risk, Less Benefit
The USPSTF shift to a more conservative recommendation on use of aspirin compared to its 2016 stance is based on new RCT data and net benefit modeling.
Phase 3 Trial Shows AZ Antibody Combination Reduces Risk of Severe COVID-19, Death in High Risk Groups
The long acting antibody combination reduced risk of severe disease or all-cause mortality by 50% in outpatients with high-risk comorbidities.
Iron Deficiency Increases Risk for Incident Coronary Heart Disease in Middle Age, Suggests New Study
Iron deficiency can't be causally linked to CHD yet, but evidence is accumulating for the association, according to authors of a new European study.
COVID-19 Updates: Delta Variant, US Vaccinations, & Global Data as of October 8, 2021
AstraZeneca Submits Request for EUA for COVID-19 Prophylaxis, AZD7442
This week, AstraZeneca submitted a request to the FDA for an emergency use authorization for their long-acting antibody cocktail for prophylaxis of COVID-19.
8 New Drugs Approved for Primary Care: Q3 2021
The first vaccine against COVID-19, 2 new treatments for migraine, a novel topical agent for atopic dermatitis, and 4 more recently approved drugs of interest to primary care.
COVID-19 Updates: Delta Variant, US Vaccinations, & Global Data as of October 7, 2021
WHO Makes Historic Recommendation for Distribution of Malaria Vaccine
WHO endorsement for widespread use in Africa of the only vaccine against malaria comes at a time when progress in control of the disease has "stalled," the organization says.
Two-dose Pfizer Vaccine Protects Against COVID-19 Hospitalization for at Least 6 Months
Two doses of the Pfizer COVID-19 vaccine also showed sustained efficacy of 93% against Delta-related hospital admission.
September Conference Roundup for Primary Care
From HIV to hypoglycemia to uncontrolled hypertension, get a recap of key clinical trials presented at IDWeek 2021, EASD 2021, and AHA Hypertension Scientific Sessions 2021.
COVID-19 Updates: Delta Variant, US Vaccinations, & Global Data as of October 6, 2021
Statin Use Associated with Diabetes Progression, Suggests New Retrospective Cohort Study
Among patients with diabetes, over 50% of statin users experienced diabetes progression vs 48% of non-statin users, according to a retrospective matched-cohort study.
For BP Monitoring, Patients Prefer Home over Clinic, Kiosk, or 24-hour Ambulatory
Clinical guidelines recommend home or ambulatory BP monitoring to diagnose hypertension. New research sheds light on what patients prefer and will adhere to.
Atrial Fibrillation Detected by ICD Linked to Ischemic Stroke within 5 Days
The temporal connection of atrial fibrillation and risk of ischemic stroke provides support for short-duration oral anticoagulation, said study authors.
COVID-19 Updates: Delta Variant, US Vaccinations, & Global Data as of October 5, 2021