Neurology

Your daily dose of clinical news you may have missed.

Variable BMI patterns across the lifespan may be a prodromal marker of dementia; a pattern of midlife increase followed by decrease was associated with greatest risk.

New Data Shows REST-LGS Screening Tool Identified Over Half of Adults with Drug-Resistant Epilepsy in Residential Care Setting Likely to Have LGS

From crime rates and credit scores to average health and hours worked in a week, find the 5 states that rank highest and the 5 lowest across 9 composite measures of stress.

The NIH has awarded $11 million for evaluation of a 5-minute, largely visual screening test for dementia intended for use in primary care practice.

Similar reduction in risk was reported for both lobar and nonlobar intracranial hemorrhage with longer statin treatment associated with greater protection, according to Danish investigators.

Being most physically active in the late morning had a 16% decreased risk of coronary artery disease and a 17% decreased risk of stroke compared to midday.

Pandemic-related stress and depression may be slowing recovery from long COVID-19 and other illnesses, according to researchers.

Your daily dose of clinical news you may have missed.

"Cardiac rehabilitation is for life," says the NYU Langone Rusk Rehabilitation medical director of cardiac/pulmonary rehab, and he advocates empathy and compassionate understanding.

New findings suggest that the elevated risk of overdose with benzodiazepine use for sleep disorders is a critical safety consideration when treating young people.

Large study comparing spinal cord stimulators to conventional medical management found a lack of clinical benefit for most patients and possible harm to some.

A daily step count of as few as 3800 was associated with a 25% reduced risk of incident dementia in a cohort of 78 000 adults; the optimal count was fewer than 10 000.

Study participants who had HZ were at 30% greater sustained risk of stroke and CHD vs those who had not had HZ in this large multicohort prospective study.

Your daily dose of clinical news you may have missed.

Study authors saw a positive dose-response relationship driven by hemorrhagic stroke in young adults who were moderate-to-heavy drinkers in their 20s and 30s.

The Nerivio REM device demonstrated a statistically significant reduction in migraine days/month vs a placebo device in both chronic and episodic migraine.

Adults with migraine with aura were found at significantly greater risk for AF and those younger than age 55 years were particularly vulnerable, write Mayo Clinic investigators.

The dextromethorphan HBr-bupropion HCI combination uses the first new oral MOA in 6 decades and is labeled to improve depressive symptoms starting at 1 week.

If the atogepant label is expanded, the drug will be the only gepant approved for the broad indication of prevention of both episodic and chronic migraine.

Episodic or chronic? Distinguishing between the 2 types of migraine is essential to ensure optimal treatment. Meet Abigail and Martin. Who has which headache?  

Treatment with intranasal insulin improved executive function and verbal memory, as well as other measures, in participants with and without type 2 diabetes.

Increasing alcohol intake from 1 to 2 drinks per day was associated with brain changes equivalent to aging 2 years, according to a study of more than 36 000.

Findings for atogepant from the phase 3 PROGRESS study will form the basis of a submission by AbbVie to FDA for a label expansion in the US.

Lifetime use of opioids for migraine was found to be higher than for triptan medications. Try these 10 questions on other OVERCOME findings.

Findings on use of acute and preventive migraine therapy continue to reveal gaps with far more patients eligible than the proportions using either type.

Researchers identified over 120 regions connected to risk of migraine, of which 86 were previously unknown.

Researchers also found that women with migraine with aura had a higher risk of preeclampsia than those with migraine without aura.

Marijuana use is linked to increased perioperative mortality among patients admitted to the hospital for cerebrovascular diagnoses, according to research presented at ISC 2022.

The 5-year cumulative relapse rate among early quitters was nearly 40% in a large international cohort of stroke patients, according to an abstract presented at ISC22.