Farshad Bagheri, MD

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Further Evidence That HTLV Protects Against HIV Progression

Farshad Bagheri, MD;Kashyapkumar Patel, MD;Naveen Pathak, MD;Vyacheslav Shamalov, MD;Jonas Gintautas, MD, PhD;Thomas Santucci, MD

September 1st 2008

Previous case reports have suggested an association betweenhuman T-cell lymphotropic virus (HTLV) types 1 and 2infection and chronic nonprogressive HIV infection. Evidenceis lacking about the specifics of how the two are related. Wereport 2 cases of chronic nonprogressive HIV infection (of9 and 13 years' duration, respectively) in women in whomHTLV coinfection was diagnosed. These cases provide clinicalsupport that HTLV coinfection may serve as a protective factoragainst progression of HIV infection. Possible reasons for thisrelationship and potential future research are discussed.[Infect Med. 2008;25:416-420]