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References: 1. Olfson M, Crystal S, Wall M, et al. Causes of death after nonfatal opioid overdose. JAMA Psychiatry. 2018.2. Oquendo MA, Volkow ND. Suicide: a silent contributor to opioid-overdose deaths. N Engl J Med. 2018;378:1567-1569.3. Seth P, Scholl L, Rudd RA, Bacon S. Centers for Disease Control and Prevention Morbidity and Mortality Report. Overdose deaths involving opioids, cocaine and psychostimulants-United States, 2015-2016. https://www.cdc.gov/mmwr/volumes/67/wr/mm6712a1.htm?s_cid=mm6712a1_w. Published March 30, 2018. Accessed July 11, 2018.4. CDC Vitalsigns. Opioid overdoses treated in emergency departments. www.cdc.gov/vitalsigns. Published March 2018. Accessed July 11, 2018.5. Dwyer-Lindgren L, Bertozzi-Vila A, Stubbs RW, et al. Trends and patterns of geographic variation in mortality from substance use disorders and intentional injuries among US counties, 1980-2014. JAMA. 2018;319:1013-1023.6. Qato DM, Ozenberger K, Olfson M. Prevalence of prescription medications with depression as a potential adverse effect among adults in the United States. JAMA. 2018;319:2289-2298. 7. Gomes T, Juurlink DN, Antoniou T, et al. Gabapentin, opioids, and the risk of opioid-related death: a population-based nested case-control study. PLOS Med. 2017;14(10):e1002396.Â