Do Brown Plaques Point to a Diabetic Disorder?

Question 1:

Several brown plaques developed on the legs of a 59-year-old woman with diabetes and pulmonary sarcoidosis; the lesions were dry and cracked in the winter but otherwise asymptomatic. Biopsy revealed a granulomatous infiltrate of epitheloid histiocytes and multinucleated giant cells surrounded by lymphocytes “layered” throughout the dermis.

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Question 2:

The newest guidelines jointly issued by the American College of Cardiology and American Heart Association in November 2013 do not provide specific target levels for lowering cholesterol, only the recommendation that statins be used to reduce it.

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Question 3:

A 44-year-old African American woman was evaluated for symptoms of worsening cough, shortness of breath, chest tightness, and fatigue of 6 months’ duration. Bronchial asthma had been diagnosed 2 years earlier. Now the diagnosis was pulmonary sarcoidosis.

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Question 4:

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Question 5:

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ANSWER KEY:

Question 1. B

Question 2. D

Question 3. E

Question 4. A

Question 5. C