The initial research findings of 2016 include a link between early elevated BMI and later diabetes and heightened dementia risk in women.
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Early elevated BMI is associated with later diabetes, dementia risk is increased in women with diabetes, lung capacity is decreased with diabetes and metabolic syndrome-these are some of the key diabetes research findings of early 2016.
Catch up here on the latest diabetes headlines.
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Early Elevated BMI Tied to Later Diabetes
• Higher body mass index (BMI) at age 21â years is associated with later diabetes incidence. Higher BMI is not linked with myocardial infarction (MI) or stroke.
• Higher BMI in middle age is strongly associated with all outcomes.
• Early obesity prevention may reduce later type 2 diabetes risk, more than MI and stroke.
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Greater Dementia Risk in Women With Diabetes
• The risk of dementia is about 60% greater in persons who have type 2 diabetes than in those who do not.
• The additional risk is greater in women with vascular dementia but not in those with nonvascular dementia.
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Lower Lung Capacity With Diabetes and Metabolic Syndrome
• Researchers investigated the dose-response relationship between pulmonary function measurements (eg, forced expiratory volume in one second [FEV1]) and risk of metabolic syndrome or type 2 diabetes.
• Lower lung capacity measurements were more prevalent in adults with 1 of the conditions. Disease risk was lowest with an FEV1 of 2.65 L to 2.76 L.
• The findings suggest screening for type 2 diabetes and metabolic syndrome in patients with obstructive lung disease and to ensure there was no abnormal glucose metabolism before the start of steroids.
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Prevent Gestational Diabetes Mellitus With Lifestyle Intervention
• The incidence of gestational diabetes mellitus in high-risk pregnant women was reduced by 39% with a moderate individualized lifestyle intervention.
• Each woman in the intervention group received counseling on diet, physical activity, and weight control from trained study nurses and had a group meeting with a dietitian.
• Women in the intervention group increased their leisure time physical activity and improved their dietary quality more than women in the control group.
• The findings may have major health consequences for mothers and their children.
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Peripheral Insulin Resistance Predicts Liver Damage in Nondiabetic Patients
• The oral glucose insulin sensitivity (OGIS) index is associated with peripheral insulin sensitivity in nonalcoholic fatty liver disease (NAFLD).
• The index is inversely associated with an increased risk of significant and advanced liver damage in nondiabetic patients with NAFLD.
• Both OGIS and NAFLD fibrosis score identified advanced (F3/F4) fibrosis, but OGIS predicted it better than NAFLD fibrosis score and was able to discriminate F2 from F3/F4.