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These 2 patients presented with a swollen hand and rapidly proximally progressive edema secondary to a bite. What creature did the biting?

A new study suggests that DNA fragmentation and progressive motility may be more accurate and consistent predictors of sperm quality than traditionally measured traits.

Results of a new large study may offer some clarity in an area replete with conflicting findings from small studies in older men or registry studies in special populations.

Current screening and treatment practices are inadequate, according to the lead author of a new study, particularly as fragility fractures among men are projected to increase 3-fold by the year 2050.

This radiograph from a 53-year-old woman revealed esophageal stricture with proximal dilatation in addition to pneumoperitoneum. Pneumatosis cystoides intestinalis (PCI) was diagnosed.

For this young physician in India, reading an article on physician suicide was “the best thing” in his day. There is one thing, he says, that keeps him moving forward.

Bumps on the face; opioids and alcohol; dysmorphic facial features in 6-month-old boy . . . questions on these and other topics in this quiz.

In the avalanche of articles that came across your desk in 2014, were there one or two that struck you as particularly noteworthy? Cast your vote here.

An occult fracture in the knee is most often a nondisplaced lateral tibial plateau fracture.

My friend has lung cancer, writes this physician. I am getting in the habit of joining him at his visits. But you shouldn’t need to bring along a doctor to protect you from your doctors.

A new study found that alcohol was involved in more than 20% of both opioid- and benzodiazepine-related deaths reported to the Drug Abuse Warning Network in 2010.

A 60-year-old homosexual man presented to the outpatient clinic with a 3-day history of facial rash associated with pain. The rash did not affect any other part of the body. He was not currently taking any immunosuppressive medication. What’s your diagnosis?

This hypersensitivity reaction may be secondary to medications, infection, collagen-vascular disorders, or an occult malignancy. When it is localized to the skin, prognosis is excellent.

What does a broken “clock gene” have to do with Alzheimer disease? Does shift work cause heart disease? Who shouldn’t be given Zolpidem for sleep? Nocturnal problems from A to Z fill round 3 of our Sleep Disorders quiz.

The older the age at which self-reported sleep disturbance was indicated, a Swedish study found, the higher the risk of Alzheimer dementia.

Here are 5 photos of non-healing ulcers: can you make the diagnosis?

Dyspnea and blood-streaked sputum; severe URI followed by rash; chronic pain; Lemierre syndrome . . . how well will you do on this quiz?