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Although spring has sprung and the peak months of respiratory virus circulation have passed, the 2022-2023 respiratory virus season has been a distinctive one. "Those of us who are involved with respiratory viruses like to say, for example, if you've seen one influenza season, you've seen one influenza season, because they're all distinctive, but this one was very special," said William Schaffner, MD, in a recent interview with 

Dr Schaffner gives a brief update on the current respiratory virus season and shares what his top challenges have been thus far, how vaccine uptake this year compares with last year, and the important role clinicians play in keeping respiratory infection and prevention on the forefront of patients minds. 

William Schaffner, MD, is medical director of the National Foundation for Infectious Diseases, professor of preventive medicine in the Department of Health Policy and professor of medicine in the Division of Infectious Diseases at Vanderbilt University School of Medicine in Nashville, TN.

 podcast features informative conversations with health care experts, opinion leaders, and prcticing physicians, about what impacts primary care medicine today. 

 to subscribe on your favorite streaming service.

William Schaffner, MD, medical director of the NFID, provides an expert recap of the 2022-2023 respiratory virus season for primary care clinicians. 

Respiratory Tripledemic 2022-23: An Expert Recap

The Primary Viewpoints podcast features informative conversations with health care experts, opinion leaders, and practicing physicians, about what impacts primary care medicine today.

In episode 15, Dr Njira Lugogo discusses the prespecified exploratory on-treatment analysis of responses to tezepelumab using data from the phase 3 NAVIGATOR clinical trial, which she recently presented at the American Thoracic Society’s International Conference 2022, held May 13-18 in San Francisco. 

Njira Lugogo, MD, is associate professor of internal medicine and director of the Asthma Program in the Division of Pulmonary and Critical Care Medicine at the University of Michigan.

 to subscribe to the Primary Viewpoints podcast. Be sure to leave a rating and review for the show. Thanks for listening!

In our latest podcast episode, Njira Lugogo, MD, discusses NAVIGATOR data she presented at ATS 2022 that showed clinical responses to treatment with tezepelumab. 

NAVIGATOR: Tezepelumab Reduces Asthma Exacerbations by More than Half

Your daily dose of the clinical news you may have missed.

Social, Racial Disparities in Flu, COVID-19, RSV Vaccine Uptake: Daily Dose

Preliminary phase 1 data showed that RSV neutralizing antibodies for non-adjuvanted SCB-1019 matched GSK’s AS01E-adjuvanted RSV vaccine, Arexvy. 

Investigational RSV Vaccine Yields Positive Preliminary Data in Head-to-Head Comparison with Arexvy

Data on adults aged 60 years and older who received a single dose of the RSV vaccine indicate safety and reactogenicity consistent with the overall GSK phase 3 trial program.  

New Data for Arexvy Show Vaccine Efficacy Through 3 RSV Seasons in Older Adults 

FDA Approves First-Ever Biologic Medicine for COPD: Daily Dose

Albuterol/budesonide (Airsupra) has now proven effective as novel combination as-needed rescue medication for adults with asthma regardless of disease severity. 

Albuterol/Budesonide Reduces Risk of Exacerbation in People with Intermittent, Mild-Persistent Asthma 

Tezepelumab, a thymic stromal lymphopoietin antagonist, 

by the FDA in December 2021 (Tezspire) as add-on maintenance therapy for patients with severe asthma whose symptoms remain uncontrolled on guideline-recommended therapy. Approval was based on findings from the phase 3 

In a presentation at the annual American Academy of Asthma, Allergy, & Immunology meeting, Tara Carr, MD, presented results of a 

 of NAVIGATOR data that assesed the efficacy of tezepelumab in a broad population of patients with severe, uncontrolled 

 comorbidities. Carr spoke with Patient Care Online about the analysis and implications for primary care practice.

is associate professor of medicine and otolaryngology, director, Adult Allergy Program and director, Allergy & Immunology Fellowship Program, Asthma and Airway Disease Research Center, at the University of Arizona College of Medicine in Tucson, Arizona. 

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Tara Carr, MD, led a post hoc analysis of the NAVIGATOR phase 3 trial and presented data on tezepelumab efficacy in the vulnerable subgroup at the AAAAI 2022 meeting.   

Tezepelumab Significantly Reduced Exacerbations in Patients with Severe Asthma, Respiratory Comorbidities 

"I think we're going to have to work very hard to get flu vaccines into arms this fall," said William Schaffner, MD, medical director of the National Foundation for Infectious Disease. 

Schaffner's concern, he explained in a recent interview with

, is that amidst the prolonged promotion around COVID-19 vaccines and now COVID-19 boosters, concerns about influenza and the danger it poses as well as the US appetite for the flu shot could all be blunted. He suggested that patients may a reminder that flu is a "nasty virus" and that clinicians may "have to, if you will, sell influenza vaccine."   

Schaffner, medical director of the National Foundation for Infectious Disease, says we need to re-educate on the dangers of flu and "sell" the influenza vaccine to the vaccine-fatigued.  


Vanderbilt’s William Schaffner, MD, says Getting Flu Shots into Arms Won’t Be Easy 

Respiratory Diseases

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