October 25th 2023
Your daily dose of the clinical news you may have missed.
What Are Pleiotropic Effects? The Role of Statins in Decreasing Inflammation
March 12th 2013It would be a mistake to attribute all beneficial outcomes obtained from statins solely to cholesterol lowering. Statins have pleiotropic effects-that is, they are simultaneously capable of producing more than one benefit, and in cardiovascular risk reduction, they accomplish more than simply lowering cholesterol.
HIV/AIDS and Starfish: "It Makes A Difference to This One"
February 20th 2013Millions of years of life have been saved by antiretroviral therapy. For more lives to be saved, for more years of life to be gained, patients and doctors need to be aware of the risk of HIV infection and to be amendable to screening.
Oroesophageal Candidiasis in a Patient With AIDS
January 18th 2013Topical treatment for oral candidiasis is not as effective when there is esophageal involvement. Topical treatments include nystatin, amphotericin B solution, and miconazole tablets. Systemic therapy given orally includes the azoles, of which fluconazole remains the most effective commonly prescribed. Voriconazole is effective against some resistant strains of Candida. Echinocandins, a newer class of drugs, inhibit cell wall synthesis.
Communicating With the IBD Patient: How to Convey Risks and Benefits
November 2nd 2011Like other chronic inflammatory conditions, inflammatory bowel disease (IBD) has been revolutionized by the advent of biologic agents that fundamentally alter the inappropriate inflammatory response. The most potent of these are the biologic agents, infliximab, adalimumab, certolizumab pegol, and natalizumab. They also have the most dangerous side-effect profile.