October 25th 2023
Your daily dose of the clinical news you may have missed.
Eosinophilic Pustular Folliculitis in an HIV-Positive Man
March 11th 2011This HIV-positive, 48-year-old man presented with new-onset acne-like, pruritic lesions on his face. These erythematous painful papules had developed 2 months before presentation. The patient was taking antiretrovirals and trimethoprim/sulfamethoxazole for the HIV infection.
Chronic Fatigue Syndrome:An Update on Diagnosis in Primary Care
February 17th 2011Chronic fatigue syndrome (CFS) is a distinct disorder characterized by debilitating and often recurrent fatigue that lasts at least 6 months but more frequently lasts for longer periods. Patients with CFS experience overall physical, social, and mental impairments and may subsequently qualify for medical disability.
Disseminated Histoplasmosis in a Woman With History of Polymyositis and Possible Dermatomyositis
November 10th 2010For 3 days, a 28-year-old woman with a history of polymyositis and possible dermatomyositis had fever, chills, and nonproductive cough. She complained of rash, joint pain, and progressive immobility because of severe muscle weakness. For the past 6 years, she had been taking prednisone (60 mg/d), hydroxychloroquine (200 mg bid), and tramadol (100 mg q6h prn for pain).
Morganella morganii Septicemia and Dermopathy
October 6th 2010A 69-year-old man with stage II chronic kidney disease due to hypertension fell from his bicycle and presented to the emergency department (ED) with abrasions, ecchymoses, and a 3-cm laceration on his right leg. The patient was an avid cyclist. His wounds were cleaned and the laceration sutured. There were no fractures, and the patient was discharged home.
Influenza Season: 2010 Vaccines
October 6th 2010This year's influenza season is approaching fast. Although the World Health Organization officially declared an end to the 2009 H1N1 influenza pandemic in August, the H1N1 virus is still circulating and is likely to continue to cause serious disease in infants, young children, pregnant women, and other high-risk groups.
Influenza Season: 2010 Vaccination Guidelines
September 23rd 2010This year’s influenza season is approaching fast. Although the World Health Organization officially declared an end to the 2009 H1N1 influenza pandemic in August, the H1N1 virus is still circulating and is likely to continue to cause serious disease in infants, young children, pregnant women, and other high-risk groups.
Unusually Severe Pharyngitis in a 19-Year-Old Woman
September 8th 2010A previously healthy 19-year-old woman presents with a sore throat that has become progressively more painful over the course of 1 week. She also has left-sided neck swelling, light-headedness, and intermittent headaches. She denies recent sexual activity.
Disseminated Mycobacterium avium-intracellulare complex Infection
June 8th 2010A39-year-old man with a history of AIDS and nonadherence to highly active antiretroviral therapy (HAART) presented with frontal headache and scalp pain of 2 weeks' duration. These symptoms were accompanied by nausea, weight loss, and generalized weakness. Physical examination revealed a small, tender scalp lump, 2 × 2 cm over the left parietal area. The findings from the rest of the examination were unremarkable.
What Physicians Can Do to Reduce Inequity in Global Health
April 24th 2010Early in his keynote address, James Orbinski, MD, Senior Fellow at the University of Toronto and one of the world’s leading scholars and scientists in global health, complimented the United States on the recent passage of its health care bill, a “seminal achievement” that he said brought the US “just a hair’s breadth away” from achieving universal health care.
Comparative Effectiveness Research-Part 2: The Impact on Decision Making
April 16th 2010As publicly funded health care payment programs have grown over decades because of demographic shifts and expansion of coverage, comparative effectiveness research (CER) has emerged to address value in health care. The American Recovery and Reinvestment Act of 2008 (ARRA) included $1.1 billion for CER initiatives, and the new health care legislation created the Patient-Centered Outcomes Research Institute, which will be funded with $500 million or more annually. In these efforts exist the promise to create informed decisions that will improve health care at both the individual and population levels.
Update on the Therapy for Sporotrichosis
March 11th 2010Sporotrichosis is a fungal infection that typically results in cutaneous or lymphocutaneous disease, although other, more severe, life-threatening manifestations do occur. This article reviews updated treatment guidelines, which state that itraconazole has become the preferred therapy for most forms of infection. Amphotericin B remains the mainstay of treatment for severe cases, but lipid formulations are now preferred because of their more favorable toxicity profile. Also, fluconazole has been shown to be less effective than itraconazole and is no longer recommended except as an alternative for cutaneous and lymphocutaneous disease. [Drug Benefit Trends. 2010;22:49-52]
Global Focus: Reports From Physician-Volunteers Around the World
February 19th 2010As a screener and admissions committee member at our medical school (University of California School of Medicine at Davis), I am privileged to review the personal statements of many, many applicants who want to be doctors in spite of the recent hard times in our country that have led more than a few American physicians to believe that our profession is less valued and less desirable as a life work than it has been in the past.
Medicare to Cover HIV Screening Tests
February 18th 2010The list of covered preventive services for Medicare beneficiaries has expanded to include screening for HIV infection, according to the Centers for Medicare and Medicaid Services. This test will now be available to Medicare beneficiaries at increased risk for HIV infection, including women who are pregnant and any Medicare beneficiary of any age who requests testing.1