Bulge Behind the Knee
No labs, no biopsies, no imaging -- only your seasoned clinical judgement is required to make a diagnosis in this case.
Hemiscrotal Bulge in an Otherwise Normal Neonate
A compressible groin swelling is the only abnormal feature after full-term gestation and unremarkable delivery. Your Dx?
Multiple Nevi on a Young Man
The teen presents for an annual physical. You note asymmetric papular lesions that cover his trunk. What is your diagnosis?
A Warty, Fungating Lesion
This lesion on the posterior neck of a young woman was present since birth and recurred after electrodessication. Can you Dx?
A Mouth Full of Gum
What is in your differential diagnosis for this lesion observed in the mouth of a 52-year-old man?
Rash Around the Mouth of a 5-year-old Child
The eruption has been present for 1 year and is restricted to the perioral region. What is included in your differential?
Acute Widespread Rash in a 9-month-old Boy
What is the cause of this erythematous rash that appeared suddenly and spread rapidly on the child's trunk and extremities?
Red in the Face
A young mother’s “high coloring” consists of papular, flesh-colored lesions that resemble telangiectasia. Can you ID?
Dyspnea and Intermittent Chest Pain in a 64-year-old Woman
Video: Patient's ADLs were unaffected by symptoms until 2 days ago. She arrives at ED directly from PCP's office, after echo. Dx?
A 13-year-old Girl with a Vesicular Rash on Palms
VIDEO: The child's hands are chronically dry but the skin has recently begun to crack; vesicular rash appeared after an ocean swim. Dx?
Progressive Rash and Arthralgias in a Teenage Male
PT Video: A short course of steroids was ineffective. He returns to ED c/o worsening joint and abdominal pain. Can you Dx?
Racing Heart, Chest Pain in a 65-year-old Man
VIDEO: Palpitations persist in ED; no history of cardiac issues. Incident is first of its kind for this patient. Watch the interview.
A 47-year-old Man with Peripheral Edema
VIDEO: Note marked tumescence in patient’s hands, pitting edema in lower extremities. Does PMH contribute? Dx?
A Young Child with a Devastating Facial Lesion
What disease, known in antiquity but largely eradicated from the developed world, caused this severe facial scarring?
Weighing Vaccine Risk vs Benefit
What is the acceptable balance between benefit and risk to prevent a vaccine's being pulled from the market? See what you recall about these 3 cases.
Head-to-Toe Rash on a 17-year-old Boy
VIDEO: The non-pruritic rash began on his chest and spread rapidly over 3 days. Get a closer look; what's your diagnosis?
Dirty Hands
The 60-year-old black woman has a history of joint pain, muscle weakness, and Raynaud phenomenon. Why the “dirty hands”?
Abdominal Pain, Altered Mental Status in a 60-year-old Woman
VIDEO: Patient reports progressive weakness x1 month. Acute abdominal pain/emesis began earlier in the day. What's in your differential dx?
A Friable Lesion on the Neck of a 15-year-old Boy: Dx?
Video: The lesion bleeds easily and grows back quickly when "knocked off."
Thumbs Up or Down on Shoulder Pain?
The patient’s reach with his thumb helps distinguish between frozen shoulder and osteoarthritis. How high is enough to tell?