Your daily dose of the clinical news you may have missed.

Shagun Bindlish, MD, board member of the American Diabetes Association, discusses challenges to diagnosing and treating venous disease in patients with obesity.

William Schaffner, MD, a long-time liaison from the NFID to the ACIP working groups, is concerned about fragmentation of US vaccine recommendations.

The FDA's ODD award is based on the positive findings from the phase 2 TouCAHn trial, which also support Crinetics' robust phase 3 pivotal clinical trial program for the novel agent.

New research confirms vaginal estradiol tablets do not increase recurrent ischemic stroke risk in postmenopausal women with a prior stroke.

A Cleveland Clinic trial revealed that AI-driven precision treatment significantly reduced HbA1c and body weight, often eliminating need for medications other than metformin.

Your daily dose of the clinical news you may have missed.

The risk for MDD is greatest in the first month after diagnosis and the absolute risk remains elevated even 20 years later, making early detection and treatment imperative.

The first oral penem antibiotic, Orlynvah™, has launched in the US, offering a vital treatment option for women with resistant uncomplicated UTIs.

This week’s roundup covers nutrition counseling barriers, tau pathology in mood disorders, RSV protection, AD patient needs, and a new Shingrix syringe.

William Schaffner, MD, advises first and foremost to stay away from politics, to acknowledge and normalize patient fear and concern, and to answer quickly and with confidence.

A recent study showed obesity in childhood or adolescence accelerates biological aging by up to 48% in young adults.

Opill OTC has significantly increased contraceptive use and shifts from less effective options among women who are uninsured, of racial/ethnic minorities, and live in the rural US.

In its updated guidelines, the AAP recommends that all children aged 6 to 23 months be vaccinated against COVID-19, citing the population's high risk for severe infection.

Your daily dose of the clinical news you may have missed.

Sarah Sams, MD, emphasizes education, empathy, and proactive communication to support families and protect public health.

Risk of dementia was more than 60% lower among adults aged 60 to 69 years with hearing loss who used hearing aids in the first study to highlight early intervention.

William Schaffner, MD, ID specialist and vaccine expert, advises following state guidance on back-to-school shots and thinking through new guidance on COVID shots for kids.

The statistically significant improvements seen in key HS symptoms during GLP-1 treatment for obesity suggest overlap in both mechanistic and immunologic effects.

New data shows more than one-third of US adults are unaware of HPV or the HPV vaccine, with gaps greatest in the Midwest and South, where HPV-related cancers are most common.

The GLP-1/GIP receptor agonist also showed promise in an exploratory maintenance arm, producing rapid weight loss at an induction dose that was sustained after down-titration.

Your daily dose of the clinical news you may have missed.

Infectious disease expert Amesh Adalja, MD, discusses new vaccine policies, misinformation, and how PCPs can build confidence during National Immunization Awareness Month.

"The foundation of science in the new iteration of the ACIP is uncertain at best," William Schaffner, MD, observed. He is concerned about where that might lead.

Family physician Sarah Sams, MD, shares practical strategies on vaccine updates, coadministration, and addressing hesitancy this respiratory season.