October 31st 2024
ACG 2024: New study results indicate GLP-1 RAs have a potentially protective role to play in combating EO-CRC, the incidence of which is notably rising worldwide.
October 10th 2024
New York City Bans Artificial Trans Fats in Restaurants
December 6th 2006NEW YORK -- The action by this city's Board of Health to ban the use of artificial trans fats in restaurants, ranging from pizzerias and delis to bakeries and upscale restaurants, could have fallout for mouths and lipid levels across the nation.
Man With GI Symptoms and Weight Loss Attributable to Primary Duodenal Adenocarcinoma
December 1st 2006A 71-year-old man presents with a2-week history of early satiety, decreasedappetite, postprandial nauseaand vomiting, jaundice, dark urine,acholic stools, and generalized pruritus.In addition, he reports a 4.5-kg(10-lb) weight loss within the past2 months.
Chest Film Clinic: What caused this man's dyspnea, chest pain, and atrial fibrillation?
December 1st 2006A 52-year-old man presented to his primary care physician with shortness of breath for 5 days, right-sided lower thoracic back pain, and dry cough. The patient was a 15-pack-year cigarette smoker who had emigrated from China to the United States in 1989. He had no significant history of occupational exposure or tuberculosis. He had no significant weight loss, and his past medical history was otherwise unremarkable.
Zenker Diverticulum in a 72-Year-Old Man
December 1st 2006A 72-year-old man was evaluated for worsening dysphagia and weight loss. The dysphagia had been intermittent for 20 years, but in the past year it had begun to occur daily. He regurgitated food after every meal, often many hours after ingestion.
A Theory Nixed for Why More Heft Means Less Premenopausal Breast Cancer
November 27th 2006BOSTON -- Cross ovulation and menstrual cycle patterns off the list for an explanation of why overweight women have less of a risk for premenopausal breast cancer, says a Harvard group. Instead, think hormonal for the perplexing protective effect.
AHA: Actos (pioglitazone) May Slow Progression of Atherosclerosis
November 14th 2006CHICAGO -- In a head-to-head trial with the sulfonylurea Amaryl (glimepiride), Actos (pioglitazone), a thiazolidinedione, appeared to slow the progression of a marker for atherosclerosis in patients with type 2 diabetes, researchers reported here.
Young Man With Fever, Headache, and Seizures
November 1st 2006A 28-year-old man is hospitalized because of highfever with rigors and chills and rapid weight loss(5.4 kg [12 lb] in 2 weeks). During the past 48 hours,generalized throbbing headache, intermittent vomiting,blurry vision, and seizures have developed. The progressiveseizures started in the left hand and have becomegeneralized grand mal.
Pulmonary arterial hypertension: Classification, diagnosis, and prognosis
November 1st 2006Abstract: Our understanding of the pathobiology of pulmonary arterial hypertension (PAH) has evolved considerably over the past 2 decades, with increasing recognition of the important role that aberrant vasoproliferative responses play in conjunction with disordered vasoconstriction. Classification of the many forms of PAH into categories sharing a similar pathophysiology and clinical presentations help the practicing clinician approach a complex differential diagnosis. Noninvasive tests can be used to narrow this differential but must be applied with an appreciation for their limitations. Transthoracic echocardiography is the screening tool of choice; the workup should also include chest radiography and electrocardiography. However, right heart catheterization is ultimately required to establish the diagnosis. While PAH remains a progressive and generally fatal disease, existing therapies have a significant impact on survival and new therapeutic targets offer great hope for improving the prognosis. (J Respir Dis. 2006;27(11):487-493)
Pulmonary Pearls: A 61-year-old woman with insidious onset of dyspnea
November 1st 2006A 61-year-old woman presented with progressive dyspnea of 5 months' duration. She first noticed dyspnea while engaged in her usual daily activities, and it gradually progressed in severity. A primary care physician prescribed bronchodilators without relief. She was subsequently referred for a pulmonary evaluation.