Colorectal Cancer

Your daily dose of the clinical news you may have missed.

Regular aspirin use was associated with a greater absolute reduction in CRC incidence among adults with unhealthier lifestyles, according to recent research.

Your daily dose of the clinical news you may have missed.

The Shield blood test is approved for primary CRC screening in adults 45 years and older at average risk for the disease.

Your daily dose of the clinical news you may have missed.

GLP-1RAs were associated with a significantly reduced risk of obesity-associated cancers including gallbladder cancer, pancreatic cancer, and meningioma.

DDW 2024. An investigational blood-based screening test demonstrated nearly a 80% sensitivity for detecting CRC, according to a large prospective study.

DDW 24. Among patients aged 15 to 19 years, the incidence of CRC rose 333% over a 22-year period, researchers reported.

Your daily dose of the clinical news you may have missed.

In average-risk individuals, the at-home ColoSense test demonstrated 93% sensitivity for detecting CRC and 45% sensitivity for detecting advanced adenomas.

New research suggests the interval "could potentially be extended" without significant harms and could reduce unnecessary invasive procedures. , ie, missed early detection and CRC-specific mortality.

The quality performance measure is viable and reliable and could help improve early CRC detection rates via timely colonoscopy following abnormal stool-based test.

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Cologuard Plus bests previous iteration and demonstrates greater sensitivity and specificity for any CRC relative to fecal immunochemical tests.

Findings from the ECLIPSE clinical trial showed the blood-based cancer screening test detects 83% of people with CRC, with a specificity of 90%.

Over 4 million cancer deaths have been reverted since 1991, but new cancer cases are estimated to reach over 2 million, according to new data from an annual American Cancer Society report.

Data from recent Austrian study suggest that sex should be considered when determining screening age for colorectal cancer, reported authors.

Your daily dose of the clinical news you may have missed.

A pivotal phase 3 clinical trial showed Cologuard significantly more likely than FIT to detect cancerous and advanced precancerous lesions.

The American College of Physicians in the updated guidance maintains the risk/benefit ratio supports screening initiation at age 50 (vs 45) years.

A combination of outreach measures tailored to the needs of rural Midwest women increased recommended screenings by as much as 6-fold.

New research shows excessive alcohol use is strongly associated with an increased risk for colorectal cancer, regardless of genetic risk.

A new study found that women who consumed ≥2 servings/day of sugar-sweetened beverages had a 2.2-fold higher risk for early onset CRC vs those who had less than 1 serving/week.

For the first time, the USPSTF recommends colorectal cancer screening in adults beginning at age 45.

A large review ties nut consumption to a lower incidence of cancer, but not diabetes.

Is a surveillance interval of 1 year, 3 years, 5, or 10 years recommended?

Certain patients with inflammatory bowel disease are at heightened risk for the development of colorectal cancer. But researchers have not yet been able to discover markers that can identify these patients.

A 47-year-old woman who recently completed adjuvant chemotherapy for colon cancer has painless cervical lymphadenopathy of 1 to 2 cm. She has no fever, sore throat, cough, or unexplained weight loss, and she denies exposure to ill persons or animals.

ABSTRACT: Screening options for colorectal cancer (CRC) include colonoscopy every 10 years, annual fecal occult blood testing, flexible sigmoidoscopy every 5 years, or double contrast barium enema every 5 years. In white patients at average risk, screening should begin at age 50; in African American patients, at age 45. Colonoscopy is preferred to sigmoidoscopy because it can detect proximal neoplasms and has the longest protection interval. High-risk patients include those with a family history of CRC or adenomas. These persons should begin colonoscopic screening at age 40, or 10 years earlier than the age at which CRC or adenomas were diagnosed in a first-degree relative. Other high-risk patients are those with a personal history of CRC, a genetic syndrome, or inflammatory bowel disease. In patients with CRC, the first follow-up colonoscopy is performed 1 year after surgery. If results are normal, the interval can be extended to every 3 years.

The FDA has approved injectable Acetadote (acetylcysteine)from Cumberland Pharmaceuticals Incto prevent or lessen liver damage resulting from an overdoseof acetaminophen. According to the FDA, unintentionalacetaminophen overdose is responsible for 100deaths and 56,000 emergency department visits per year.