Atrial Fibrillation

GAINESVILLE, Fla. -- Hispanic women with coronary artery disease and hypertension achieved better blood pressure control than non-Hispanic white counterparts who were treated with the same antihypertensive drugs.

EDMONTON, Alberta -- Phosphodiesterase type 5 (PDE5) drugs, such as sildenafil (Viagra), may improve right ventricular contractility in hearts with right ventricular hypertrophy, an unexpected benefit that looks promising for treatment of right ventricular heart failure.

LORENSKOG, Norway -- B-type natriuretic peptides have earned a new vote of confidence as a prognostic biomarker for low-risk patients with stable coronary disease.

SANTA MONICA, Calif. -- When patients have to pay more for their prescriptions, spending on drugs goes down, but so does adherence, a new study shows.

GENEVA -- Airline travel that lasts four hours or longer is associated with a one in 6,000 absolute risk of developing venous thromboembolism, according to the World Health Organization.

* Vena caval interruption has been used in the treatment of deep venous thrombosis (DVT) to prevent PE since the early 1970s. Filter placement has been increasing in the past decade. We estimate that filters are placed in more than 0.2% of all Medicare recipients annually.

Heart failure is prevalent in both primary care and cardiology practices. It develops in about 1 in 5 persons during their lifetime and in about 1 in 8 of those who have not sustained a myocardial infarction (MI). Heart failure is also the leading cause of hospitalization in the elderly.

Your Observations About the Man With the Tripod Sign

A 67-year-old woman arrived via ambulance in ventricular tachycardia. She had been experiencing crushing substernal chest pain and shortness of breath that had worsened over the past several hours. She received oxygen (by mask) and lidocaine (100 mg intravenously) en route to the emergency department (ED), but there was no change in the rhythm.

CHICAGO -- Metabolic syndrome and its components helped predict mortality for diabetic and non-diabetic patients alike, independently of Framingham cardiovascular risk, researchers found.

CHICAGO -- When the spotlight here focused on rosiglitazone (Avandia) and its harshest critic, Steven E. Nissen, M.D., of the Cleveland Clinic, the cardiologist offered a mild apology to a room full of diabetologists for complicating their lives.

SEATTLE -- Severe diastolic dysfunction tops all other echocardiograhic measures as a post-MI prognostic marker, investigators reported here.

BALTIMORE -- Most of the 5,000 hospitals that care for Medicare patients meet the national average for 30-day mortality from MI or heart failure, Centers for Medicare & Medicaid Services (CMS) data show.

SEATTLE -- A hand-held echocardiography device can bring cardiac imaging to the outpatient setting, said investigators here.

TORONTO -- An investigational oil-and-water adjuvant for flu vaccines -- tested in conjunction with a vaccine against avian flu -- is safe, a researcher said here.

SEATTLE -- Appropriately trained nurses can supervise stress echocardiograms with no more risk than in physician-supervised tests, a review of 15,404 nurse-monitored tests suggests.

HOUSTON -- Myocardial infarction and other acute cardiac events closely track pneumococcal pneumonia, which suggests a need for multiple admitting diagnoses.

SEATTLE -- Stress echocardiography can help spot women suspected to be at a high risk for coronary artery disease, investigators reported here.

SALT LAKE CITY-- Amputations of frostbite-damaged fingers and toes can be prevented in some patients with the use of thrombolytic therapy within 24 hours of exposure, researchers here found.

EDMONTON, Alberta -- For patients with stable heart failure, cardiac rehabilitation that focuses on aerobic training can reverse left-ventricular remodeling and improve ejection fraction

ROTTERDAM, The Netherlands -- Before heart disease even develops among patients with heart disease, the effects on life expectancy have already begun, found researchers here.

PORTO, Portugal -- As metabolic syndrome becomes more severe, symptomatic heart failure and several cardiac structural and functional abnormalities may increase progressively, researchers here reported.

OXFORD, England -- Statin drugs are highly effective and are generally safe when used as indicated, a literature review confirmed.

WASHINGTON -- FDA Commissioner Andrew C. von Eschenbach, M.D., today told a congressional hearing that the FDA will beef up the cardiovascular warnings on the labels of both rosiglitazone (Avandia) and pioglitazone (Actos).

ATLANTA -- Credit for the near halving of the rate of coronary disease deaths in the U.S, from 1980 to 2000, belongs equally to reductions in risk factors and to the rise of evidence-based therapies, found CDC and British researchers.

CHICAGO -- Bevacizumab (Avastin) added to chemotherapy for bulky small-cell lung cancer led to modest anticancer activity without clinically significant hemoptysis, investigators reported here.

NEWCASTLE UPON TYNE, England, June 5 -- An interim analysis of the 4,447-patient RECORD trial did not confirman increased risk of myocardial infarction or cardiac death in patients taking rosiglitazone (Avandia) for treatment of type 2 diabetes, although the data suggest an increased risk of heart failure. So reported the New England Journal of Medicine online today, one day before a Congressional hearing on the safety of rosiglitazone.

ABSTRACT: Atypical clinical presentations in the quality, intensity, and radiation of pain are common in patients with acute coronary syndromes. Women with an acute myocardial infarction (AMI) are more likely to have atypical symptoms, such as dyspnea, than men. A history of acute anxiety or a psychiatric diagnosis does not preclude the possibility of an acute coronary event in a patient with chest pain. The clinical response to a GI cocktail, sublingual nitroglycerin, or chest wall palpation does not reliably identify the source of pain. Over-reliance on tests with poor sensitivity, such as the ECG, or on the initial set of cardiac biomarkers will miss many patients with MI. Serial troponin levels obtained at 3- to 6-hour intervals are recommended to evaluate the extent of myocardial damage. Coronary angiography that detects mild non-obstructive disease does not exclude the possibility of sudden plaque rupture and acute coronary occlusion.

Torsades de pointes, or polymorphic ventricular tachycardia, seen on ECG includes wide complex QRS morphology tachycardia, axis deviation of the QRS complexes around baseline.

abstract: Inflammatory bowel disease (IBD) can have a variety of extraintestinal manifestations, including pulmonary disease. Bronchial involvement is the most common, but other manifestations include upper airway disease; parenchymal involvement, such as bronchiolitis obliterans with organizing pneumonia (BOOP) and interstitial lung disease; and serositis, including pleural effusions and pericarditis. Patients with BOOP may present with fever, dyspnea, cough, and pleuritic chest pain. Chest radiographs show bilateral patchy airspace opacities or a diffuse process; CT scans often demonstrate the opacities to be pleural-based. Corticosteroids appear to be effective in the management of certain pulmonary manifestations of IBD, such as BOOP and pulmonary infiltrates with eosinophilia. (J Respir Dis. 2007;28(6):227-234)