Test Your HCV IQ: 5 Quick Questions

When to test, how long to treat, adjustments needed to avoid dangerous drug interactions -- test your HCV IQ with a short quiz on a range of topics.

1. What is the shortest duration of treatment that can be used to treat HCV while achieving >95% sustained virologic response rates?A. 6 weeks

B. 8 weeks

C. 12 weeks

D. 24 weeks

Please click below for answer and next question.

The correct answer is B. 8 weeks

**********************************

2. Which of the following tests is not absolutely required prior to initiating treatment for HCV with the direct-acting agents (DAAs):

A. HCV RNA by PCR

B. HCV genotype

C. HCV fibrosis assessment

D. HCV resistance test
 

Please click below for answer and next question.

The correct answer is D. HCV resistance test

**********************************

3. How soon after exposure to HCV can HCV RNA can be detected in the blood using a nucleic acid test (NAT assay)?A. 5 to 7 days after exposure

B. 1 to 2 weeks after exposure

C. 2 to 3 weeks after exposure

D. 3 to 4 weeks after exposure

 

Please click below for answer and next question.

The correct answer is B. 1 to 2 weeks after exposure

****************************

4. Which one of the following drugs/components of HCV treatments needs to be adjusted if a patient is on medications that are cytochrome p450 3A/4 inducers or inhibitors?A. Sofosbuvir

B. Velpatasvir

C. Paritaprevir

D. Daclatasvir

Please click below for answer and next question.

The correct answer is D. Daclatasvir (needs to be adjusted if a patient is on medication that induces/inhibits cytochrome p450 3A/4).

****************************

5. Which of the following classes of FDA-approved HCV drugs has a high intrinsic barrier to the development of resistance?A. NS5B non-nucleoside polymerase inhibitors

B. NS5A inhibitors

C. NS3/4A protease inhibitors

D. NS5B nucleoside polymerase inhibitors
 

Please click below for answer.

The correct answer is D. NS5B nucleoside polymerase inhibitors

Resources

Hepatitis C and Primary Care: Introduction

Hepatitis C Report: Tuning in to a Silent Epidemic

Hepatitis C Screening for High Risk Patients

Hepatitis C Report: What Tests to Order

Medicaid Is Tight on Hepatitis C Drug Coverage

Newer Hepatitis C Drugs Mean Direct Action

Hepatitis C Drugs Meet Resistance Issues