- CDC
- Heart Failure
- Cardiovascular Clinical Consult
- Adult Immunization
- Hepatic Disease
- Rare Disorders
- Pediatric Immunization
- Implementing The Topcon Ocular Telehealth Platform
- Weight Management
- Screening
- Monkeypox
- Guidelines
- Men's Health
- Psychiatry
- Allergy
- Nutrition
- Women's Health
- Cardiology
- Substance Use
- Pediatrics
- Kidney Disease
- Genetics
- Complimentary & Alternative Medicine
- Dermatology
- Endocrinology
- Oral Medicine
- Otorhinolaryngologic Diseases
- Pain
- Gastrointestinal Disorders
- Geriatrics
- Infection
- Musculoskeletal Disorders
- Obesity
- Rheumatology
- Technology
- Cancer
- Nephrology
- Anemia
- Neurology
- Pulmonology
Pyoderma Gangrenosum: Clinical Manifestations
This painful, eroded plaque on thedorsum of a 39-year-old man’s handhad developed over a few days from asmall, painful pustule. The patient’shistory included ulcerative colitis,which was not active when the lesionoccurred.
Case 4:Man With Ulcerative Colitis
This painful, eroded plaque on thedorsum of a 39-year-old man's handhad developed over a few days from asmall, painful pustule. The patient'shistory included ulcerative colitis,which was not active when the lesionoccurred.
After being admitted to the hospital,the patient was given intravenousantibiotics; however, after 3 daysof therapy, no improvement wasnoted. Bacterial cultures showed nogrowth. A biopsy of the lesion supportedthe clinical diagnosis of pyoderma gangrenosum.The patient's history of ulcerative colitis was a clue tothe diagnosis; the destructive cutaneous ulcers can occureven when the inflammatory bowel disease is inactive.Early pyoderma gangrenosum may mimic cellulitis.
The ulcer responded dramatically to systemic corticosteroids.Following a single recurrence of pyodermagangrenosum, the patient has been free of the disease forthe past 3 years.
(Case and photograph courtesy of Dr David L. Kaplan.)
