Drug-Associated Pancreatitis

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There are 3 classes of medications associated with pancreatitis. Class 3 drugs have been rarely implicated; diphendydramine has not been implicated with pancreatitis to date.

All of the following drugs have been associated with pancreatitis except. . . ?

a. Azathioprine
b. Opiates
c. Diphenhydramine
d. Rifampin
 

Answer: C

There are 3 classes of medications associated with pancreatitis. Class I medications-those that have been reported in at least 20 case reports-include opiates and azathioprine. With class II medications, between 10 and 20 cases have been reported; this includes rifampin. Class 3 drugs have been rarely implicated; diphendydramine has not been implicated with pancreatitis to date. 
 

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