Hypertension Management in Patients with Obesity: 3 Pearls for Primary Care
Caissa Troutman, MD, shares 3 key strategies for managing hypertension in patients with obesity in primary care.
Prioritizing Blood-Based CRC Tests May Lead to Higher Costs and Worse Outcomes, Study Finds
Annual colorectal cancer screening with FIT was the most cost-effective strategy among patients with low adherence, researchers reported.
Medicare Part D Phase 2 Price Negotiations Target Semaglutide (Wegovy) Plus 14 More
Price negotiations, effective in 2027, cover drugs for diabetes, cancer, COPD, and more, aiming for substantial Medicare savings.
Semaglutide 7.2 mg Achieves Weight Reduction of 21% in Late-Stage STEP UP Trial
The 20.7% weight loss with the high-dose of semaglutide bested the mean reduction of 17.5% seen with semaglutide 2.4 mg, according to Novo Nordisk.
FDA Approves First Generic Daily GLP-1 Injection for Type 2 Diabetes: Daily Dose
Your daily dose of the clinical news you may have missed.
DEA Amends Telehealth Prescribing Rules, Including Special Registration for Schedule II-V Medications
The DEA action includes 3 new telehealth rules that make permanent several flexibilities enacted during the pandemic and also establish new protections for patients.
Obstructive Sleep Apnea and Hypertension Update: FDA Clears Phase 2 Trial of Lorundrostat, an Oral Aldosterone Synthase Inhibitor
Mineralys Therapeutics also expects topline data from its phase 2 study of lorundrostat for the treatment of uncontrolled hypertension or resistant hypertension when used as an add-on therapy.
Machine Learning Identifies Risk Factors for Severe Cognitive Decline During Menopause
The effective approach to identifying risk for the disruptive cognitive issues holds promise for development of early intervention to mitigate decline.
Novel Tool Predicts Onset Age of Cognitive Impairment and Alzheimer Dementia
The Florey Dementia Index showed robustness across different cohorts but more testing is needed, researchers reported.
FDA Proposed Rule Would Limit Nicotine Content in Cigarettes, Cigars, Other Combusted Products
The agency estimates that limiting nicotine levels could lead to 1.8 million fewer tobacco-related deaths by 2060 and health care savings of $1.1 trillion a year over the next 40 years.
CAH Update: High-Level Examination of Condition Published in Expert Review of Endocrinology & Metabolism, Neurocrine Announces
"Glucocorticoid therapy in classic congenital adrenal hyperplasia: traditional and new treatment paradigms," offers an in-depth look at the disorder and promising therapies.
Obesity and Hypertension: Addressing Misconceptions in Clinical Practice
Caissa Troutman, MD, stresses the importance of building trust with patients through active listening and consistent, non-judgmental communication.
ACG Updates Guidelines for Eosinophilic Esophagitis: Daily Dose
FDA Approves Lilly’s Mirikizumab-mrkz for Crohn’s Disease
Marketed as Omvoh, the therapy is already approved as a first-in-class treatment for moderately to severely active ulcerative colitis.
Atopic Dermatitis pipeline: IND Application Cleared by FDA for Novel Monoclonal Antibody OX40 Antagonist
Early proof-of-concept phase 1a data from the trial is anticipated in the third quarter of 2025.
USPSTF Issues Final Recommendations on Osteoporosis Screening to Prevent Fractures
The USPSTF recommends all women ages 65 and older and at-risk postmenopausal women under 65 should be screened for osteoporosis.
GLP-1/GIP Dual Agonist HRS9531 Shows Promising Phase 2 Data for Obesity Management
More than half of study participants receiving the dual incretin agonist had weight loss of 20% or greater, with no evidence of a plateau and only mild AEs.
Elinzanetant VMS update: As Positive Results Pile Up, Bayer Readies for Menopause Treatment’s Future
FDA action date set for July 26, 2025.
Overcoming Barriers in Obesity and Hypertension Management: Practical Strategies for Physicians
Caissa Troutman, member of the Obesity Medicine Association, emphasizes the importance of shared decision-making in overcoming barriers to managing hypertension and obesity.
Higher Daily Step Count Linked to Lower Risk for Depression: Daily Dose
