Alpine skiing, snowboarding, bobsledding, ice hockey … the ongoing Winter Olympics in Sochi serve as a cold reminder that injuries plague athletes around the world. Test your knowledge of common sports injuries here.

This 20-year-old woman has one blue and one brown iris. To what genetic disorder might this finding point?

California has introduced legislation that would require cigarette-package-type warnings on containers of sugary soda. Tell us what you think about the move.

A 17-year-old woman presents with a gradually increasing, asymptomatic “sore” on her lower lip. What’s your impression?

At-hand reminders to check blood sugar or refill a prescription may be just what the doctor needs to order.

There are no guidelines on how to differentiate iatrogenic opioid abuse triggered by treatment for legitimate pain from illicit use. And yet, theories abound.

For 2 months, a 29-year-old man had pain and circular, soft swelling (7 x 7 cm in diameter) over the anterior left knee, superficial to the patellar ligament. Your dx?

There are currently 3 sets of guidelines that outline the management of thyroid nodules. A case in point here.

Would you biopsy a 1-cm mobile nodule in the thyroid area of this 55-year-old woman who had mantle field radiation for a childhood cancer?

HIV-positive status no longer equates with emaciation. In fact, if anything, patients are more likely to be over- than under-weight, and this can affect the success of their treatments. Here, some guidance for clinicians on how to address the issue.

A 32-year-old man with no significant medical history presents with multiple scrotal lesions that he claims have been present for 2 years. They are non-tender and he reports no overt symptoms. The full case, here.

Depression is common among HIV-positive patients, and clearly affects adherence. Treating depression improves adherence, but is also justified in its own right as improperly treated depression can be as devastating as inadequately treated AIDS.

(AUDIO) In a brief podcast, the director of the University of North Carolina infectious diseases center ponders the implications of new HIV strains that lead to AIDS symptoms significantly faster than in the past. To him, the response is obvious. What troubles him is that not everyone seems to sense the urgency

Physicians are no strangers to the pen and have made invaluable contributions to world literature. Here, the story of a 21st-century internist-author who is firmly rooted in both worlds.

A 27-year-old woman intermittently experiences painful oral lesions such as this one on her upper lip. Your impression?

Headaches have been awakening a man in his mid-40s at about 3 in the morning for a period of 2 weeks. On this, his second visit to the ED for the symptom, he claims numbness in one arm and reports vomiting earlier that evening. More details of the case, here.

A 34-year-old woman presents for follow-up of her type 2 diabetes mellitus and starts therapy with lisinopril. She thinks she also may be pregnant. What is the problem?

A beautiful baby with a yellow plaque. . . . idiopathic chilblains . . . 5 questions here to challenge you.