Dermatology

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Asymptomatic lesion on the dorsum of a 15-year-old boy’s left hand extends on to the first 2 fingers and has produced nail dystrophy. The patient is otherwise healthy and denies any history of trauma to the hand.

The mother of a 10-year-old boy brings him in for evaluation of his moles (which are all benign). During the visit, the mother asks about the lesions on the first 2 knuckles of his right hand; she initially noticed them several months earlier.

A 26-year-old white male aviator presents to his primary care physician for his annual military physical examination. The patient is healthy, takes no medications, and has no history of serious medical disorders. Genital examination reveals multifocal, confluent, slightly variegated, hyperpigmented macules with irregular borders located in a circumferential distribution on the penile shaft and glans.

A 37-year-old man presented to the emergency department with painful, burning, blistering skin lesions. The lesions started 3 days earlier on the face and spread to the trunk and extremities. Ten days before presentation, the patient had received a diagnosis of AIDS.

Not for Women Only

Men who have undergone localprocedures in the genital or analarea (eg, abscess drainage) find itdifficult to get a bandage to adhereto the skin because of the pubichair.

For 5 days, a 68-year-old woman has been bothered by a painful swelling on her left cheek. There is no history of trauma or bite. She takes a diuretic for mild hypertension. Amoxicillin/clavulanate was started 2 days earlier pending the results of a bacterial culture.What is the likely diagnosis?

Eczema is confined to the dorsum of a 37-year-oldwoman’s hands. She had been applying an over-thecounter,topical antifungal cream but noted no changein the rash. The patient is a hairdresser and enjoyskickboxing.

Chronic plaque psoriasis in this 37-year-old man was treated with systemic corticosteroids after topical medications proved ineffective. The corticosteroids provided initial relief, but the psoriasis recurred once the medication was discontinued. This patient had been in a county jail for about 18 months; during his confinement, he was not exposed to sunlight.

A previously healthy 40-year-old man complains of worsening lower-extremity discomfort. He noticed the discomfort several days earlier on awakening and thought that he had been bitten by a spider. The lesion, initially a small pustule, has enlarged into an open wound.

A 16-year-old boy with asymptomatic, hyperpigmented, hairy lesion on his left upper back. The pigmentation, first noted 5 years earlier, had progressively spread across his torso. The coarse and dark hair confined to the hyperpigmented area had appeared at age 13 years. Medical history uneventful. Review of systems showed no abnormalities. No family history of similar skin lesions.

Read Between the Lines

When a patient complains of a “sore that won’t heal” or mentions that a lesion “constantly bleeds and scabs,” heed the advice of Osler.

For 9 months, a 39-year-old woman has had a pruritic rash on the posterior portion of one thigh. She had consulted another physician, who prescribed a medication that she does not recall, but there was no improvement.

These scaly plaques on the scalp of a 32-year-old man have failed to respond to a topical antifungal. The patient has a 3-year history of pulmonary sarcoidosis.

A 24-year-old man is concerned about a large, hairy "mole" on his left shoulder. The lesion appeared during adolescence as a group of small, dark blotches. These eventually coalesced into a hyperpigmented patch with hair and acne.

During a routine checkup, a 14-year-old girl inquires about a large red spot on her right ankle. The asymptomatic, erythematous area overlying the malleolus has been present for several months.