December 6th 2018
Patient claims pruritic full-body rash is from a course of vancomycin. Is he correct? Could it be something else?
Middle-Aged Man with Polyuria and Penile Swelling and Pain
November 1st 2007For 2 weeks, a previously healthy 40-year-old man has had excessive thirst and increased frequency of urination. He awakens at least 5 times every night to urinate. He reports no nausea, vomiting, change in bowel habits, chest pain, or dyspnea.
What Cause of Cold and Flushing in a Basketball Player?
November 1st 2007A 20-year-old white male collegiate basketball player has a 3-year history of marked facial and upper extremity flushing that occurs after about 20 minutes of indoor practice. The flushing is preceded by an intense sensation of coldness, and despite the very noticeable flushing, the involved areas are cold to the touch for some time.
Pyoderma Gangrenosum on Both Legs of a 62-Year-Old Woman
November 1st 2007Worsening painful ulcers on both legs prompted a 62-year-old woman to seek medical attention. She had a history of rheumatoid arthritis (RA), demonstrated by the markedly deformed interphalangeal joints in her thumbs (A), and scleroderma-polymyositis overlap syndrome.
Secondary Syphilis and HIV Positivity
November 1st 2007Six months after testing positive for HIV in 10 bands, a 24-year-old homosexual man presented with a macular rash on his palms and soles. He first noticed the lesions 2 weeks earlier; they were not pruritic or painful. He also had a brighter, more inflamed rash in the groin and antecubital fossae that was presumed to be a yeast infection and was treated with fluconazole. He had no other symptoms.
Emerging Infections:What You Need to Know, Part 1
October 1st 2007Within the past 7 years, the incidence of methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium difficile infections has significantly increased. Risk factors for MRSA infection include previous antibiotic therapy and living arrangements such as prisons or military barracks that involve close, frequent contact with infected persons. Treat stable patients with MRSA skin infections with oral antibiotics in addition to incision and drainage; hospitalization and intravenous antibiotics are recommended for patients whose condition is unstable or who are unlikely to adhere to an oral regimen. A new strain of C difficile, BI/NAP1, has been associated with recurrent infection; more severe disease that mandates urgent colectomy; and dramatically higher mortality in vulnerable populations, such as older adults. Although oral metronidazole has been the mainstay of treatment of C difficile infection, oral vancomycin may be slightly more effective in patients with severe disease.
Keratoacanthoma Resembling Squamous Cell Carcinoma
October 1st 2007An 89-year-old man reported that this lesion began developing on his left forearm 11 days earlier. It is a keratoacanthoma, a rapidly growing but benign neoplasm that occurs predominantly on the extensor surfaces of the hands and forearms of white men over age 50.
Small-Bowel Metastatic Melanoma
September 1st 2007An 83-year-old man with a history of hypertension, hyperlipidemia, and diverticulosis was hospitalized because of painless hematochezia of 1 day's duration. Two years earlier, he had undergone surgical excision of a superficial spreading melanoma on his right thigh.
Porphyria Cutanea Tarda in a Construction Worker
September 1st 2007For several months, a 55-year-old white construction worker experienced intense burning of the skin when exposed to direct sunlight. In addition, multiple fragile blisters appeared on the dorsa of his hands and arms; these rapidly developed into crusted, superficial erosions.